Mammalian copper homeostasis: Physiological roles and molecular mechanisms

S Lutsenko, S Roy, P Tsvetkov - Physiological reviews, 2025 - journals.physiology.org
In the past decade, evidence for the numerous roles of copper (Cu) in mammalian
physiology has grown exponentially. The discoveries of Cu involvement in cell signaling …

Cuproptosis in lung cancer: mechanisms and therapeutic potential

Q Li, T Wang, Y Zhou, J Shi - Molecular and cellular biochemistry, 2024 - Springer
Cuproptosis, a recently identified form of cell death that differs from other forms, is induced
by the disruption of the binding of copper to mitochondrial respiratory acylation components …

Pan-cancer genetic analysis of cuproptosis and copper metabolism-related gene set

H Liu, T Tang - Frontiers in oncology, 2022 - frontiersin.org
Background A recent paper has revealed a novel cell death pathway, cuproptosis, a
programmed cell death based on copper. This study aimed to evaluate the pan-cancer …

Novel COX11 Mutations Associated with Mitochondrial Disorder: Functional Characterization in Patient Fibroblasts and Saccharomyces cerevisiae

CA Caron-Godon, S Della Vecchia, A Romano… - International Journal of …, 2023 - mdpi.com
Genetic defects in the nuclear encoded subunits and assembly factors of cytochrome c
oxidase (mitochondrial complex IV) are very rare and are associated with a wide variety of …

The Escherichia coli MFS-type transporter genes yhjE, ydiM, and yfcJ are required to produce an active bo3 quinol oxidase

B Khalfaoui-Hassani, CE Blaby-Haas, A Verissimo… - Plos one, 2023 - journals.plos.org
Heme-copper oxygen reductases are membrane-bound oligomeric complexes that are
integral to prokaryotic and eukaryotic aerobic respiratory chains. Biogenesis of these …

SsCox17, a copper chaperone, is required for pathogenic process and oxidative stress tolerance of Sclerotinia sclerotiorum

Y Ding, Y Chen, Z Wu, N Yang, K Rana, X Meng, B Liu… - Plant Science, 2022 - Elsevier
Stem rot, caused by Sclerotinia sclerotiorum has emerged as one of the major fungal
pathogens of oilseed Brassica across the world. The pathogenic development is exquisitely …

Characterisation of cytochrome c oxidase-coding genes from mung bean and their response to cadmium stress based on genome-wide identification and …

Y Leng, ZB Niu, SH Liu, FJ Qiao, GF Liu… - Molecular Biology …, 2025 - Springer
Background Cytochrome c oxidase (COX) is a crucial mitochondrial enzyme in the electron
transport chain of plants, implicated in energy production and stress responses. Despite its …

[PDF][PDF] Genetic inactivation of mitochondrial complex IV in Physcomitrium patens unveils the relevance of respiration for efficient carbon and nitrogen metabolisms in …

AM Vera-Vives, M Mellon, L Gurrieri, A Segalla… - … THE ROLE OF … - research.unipd.it
In photosynthetic organisms, respiration is needed to support metabolism during the night
and in non-photosynthetic tissues, but it also plays a fundamental metabolic role in the light …