Events in fetal life impact long-term health outcomes. The placenta is the first organ to form
and is the site of juxtaposition between the maternal and fetal circulations. Most diseases of …

Uveitis is a group of diseases characterized by intraocular inflammation, of which some are
driven by autoinflammatory or autoimmune responses, such as Vogt-Koyanagi-Harada …

Human leucocyte antigen B* 27 (HLA-B* 27) is strongly associated with inflammatory
diseases of the spine and pelvis (for example, ankylosing spondylitis (AS)) and the eye (that …

The axial spondyloarthritis (axSpA) disease concept has undergone substantial change
from when the entity ankylosing spondylitis was defined by the modified New York criteria in …

Ankylosing spondylitis (AS), an immune-mediated arthritis, is the prototypic member of a
group of conditions known as spondyloarthropathies that also includes reactive arthritis …

Radiographic axial spondyloarthritis (also known as ankylosing spondylitis [AS]) is a chronic
immune-mediated arthritis characterized by inflammation of the axial skeleton, peripheral …

Acute anterior uveitis (AAU) and the spondyloarthritis (SpA) subtypes ankylosing spondylitis,
reactive arthritis and psoriatic arthritis are among the inflammatory diseases affected by the …

Summary The interleukin 1 (IL-1) pathway signals through IL-1 receptor type 1 (IL-1R1) and
emerges as a central mediator for systemic inflammation. Aberrant IL-1 signaling leads to a …

Uveitis is the most frequent extra-articular manifestation of axial spondyloarthritis (SpA),
occurring in up to one-third of the patients. In the majority of patients, uveitis is acute, anterior …

Uveitis is a common complication of spondyloarthritis. The “phenotype” of the uveitis
characteristic of ankylosing spondylitis (sudden onset, anterior, unilateral, recurrent, more …