Novel agents are required to increase the radiosensitivity of cancer and improve the
outcome of radiotherapy. Thioredoxin (Trx) and thioredoxin reductase (TrxR) reduce the …

Simple Summary Appropriate testing models are imperative to facilitate the discovery of
effective personalized treatments against different cancers, including advanced cervical …

Radiotherapy (RT) stands as a cornerstone in the clinical armamentarium against various
cancers due to its proven efficacy. However, the intrinsic radiation resistance exhibited by …

In recent years, biologists and clinicians have witnessed prominent advances in in vitro 3D
culture techniques related to biomimetic human/animal tissue analogs. Numerous data have …

Background/Aim: Osteosarcoma (OS) is a rare malignant tumor with a poor survival rate. Our
previous study reported that auranofin (AUR), a thioredoxin reductase inhibitor, suppresses …

Background/Aim: Auranofin (AUR), a thioredoxin reductase (TXNRD) inhibitor, shows
anticancer activity against several cancers. This study investigated the effects of AUR on the …

Simple Summary Breast cancer is one of the most commonly diagnosed cancers worldwide
and remains a leading cause of cancer-associated death in women. Radiation therapy is …

Background. Aerobic organisms continuously generate small amounts of Reactive Oxygen
Species (ROS), which are involved in the oxidation of sensitive cysteine residues in proteins …

Objective: There is currently a wide range of cleansing and irrigation solutions available for
wounds, many of which contain antimicrobial agents. The aim of this study was to assess the …

OBJECTIVE The anticancer properties of curcumin were determined in several studies, but
on breast cancer stem cells (BCSCs) derived from a heterogeneous population of tumor …