Endothelial mitochondria play important signaling roles critical for the regulation of various
cellular processes, including calcium signaling, ROS generation, NO synthesis or …

In this study the co-assembly of two amphiphilic block copolymers with tailored composition
and molecular characteristics, poly (ethylene oxide)-poly (ε-caprolactone)-b-poly (ethylene …

Statins belong to the most often prescribed medications, which efficiently normalise
hyperlipidaemia and prevent cardiovascular complications in obese and diabetic patients …

An increased concentration of palmitate in circulation is one of the most harmful factors in
obesity. The von Willebrand factor (vWF), a protein involved in haemostasis, is produced …

The influence of glucose and palmitic acid (PA) on mitochondrial respiration and emission of
hydrogen peroxide (H2O2) was determined in skeletal muscle‐derived microvascular …

This study aimed to investigate the putative role of nicotinamide N-methyltransferase in the
metabolic response of human aortic endothelial cells. This enzyme catalyses S …

Previously we showed that a mild stimulation of EA. hy926 cells with tumour necrosis factor
alpha (TNFα) activated mitochondrial biogenesis, probably as a mechanism preventing cell …

While atRA canonically enacts gene transcription through the CRABP2/RAR signaling
pathway to induce anti-carcinogenic effects, it is also able to act through the FABP5/PPARδ …

Abstract Treatment of endothelial cells with bacterial lipopolysaccharide (LPS) evokes a
number of metabolic and functional consequences which built a multifaceted physiological …

Nutrient excess is associated with many non-communicable diseases, including obesity,
T2D, CVDs, and dementias3, 4. Nutrient excess-associated diseases share common …