PPAR gamma gene–a review

C Janani, BDR Kumari - … & Metabolic Syndrome: Clinical Research & …, 2015 - Elsevier
Peroxisome proliferator-activated receptor gamma (PPARγ) has been the focus of intense
research because ligands for this receptor have emerged as potent insulin sensitizers used …

New developments in adipogenesis

MI Lefterova, MA Lazar - Trends in Endocrinology & Metabolism, 2009 - cell.com
The obesity epidemic has focused attention on adipose tissue and the development of fat
cells (ie adipocytes), which is known as adipogenesis. Peroxisome proliferator-activated …

Single-cell map of diverse immune phenotypes in the breast tumor microenvironment

E Azizi, AJ Carr, G Plitas, AE Cornish, C Konopacki… - Cell, 2018 - cell.com
Knowledge of immune cell phenotypes in the tumor microenvironment is essential for
understanding mechanisms of cancer progression and immunotherapy response. We …

PPARγ and C/EBP factors orchestrate adipocyte biology via adjacent binding on a genome-wide scale

MI Lefterova, Y Zhang, DJ Steger… - Genes & …, 2008 - genesdev.cshlp.org
Peroxisome proliferator-activated receptor γ (PPARγ), a nuclear receptor and the target of
anti-diabetic thiazolinedione drugs, is known as the master regulator of adipocyte biology …

Intermuscular and intramuscular adipose tissues: Bad vs. good adipose tissues

GJ Hausman, U Basu, M Du, M Fernyhough-Culver… - Adipocyte, 2014 - Taylor & Francis
Human studies of the influence of aging and other factors on intermuscular fat (INTMF) were
reviewed. Intermuscular fat increased with weight loss, weight gain, or with no weight …

Aging in adipocytes: potential impact of inherent, depot-specific mechanisms

MJ Cartwright, T Tchkonia, JL Kirkland - Experimental gerontology, 2007 - Elsevier
Fat mass and tissue distribution change dramatically throughout life. Fat depot sizes reach a
peak by middle or early old age, followed by a substantial decline, together with fat tissue …

[HTML][HTML] Bone marrow adipocytes promote tumor growth in bone via FABP4-dependent mechanisms

MK Herroon, E Rajagurubandara, AL Hardaway… - Oncotarget, 2013 - ncbi.nlm.nih.gov
Incidence of skeletal metastases and death from prostate cancer greatly increases with age
and obesity, conditions which increase marrow adiposity. Bone marrow adipocytes are …

A global perspective on FOXO1 in lipid metabolism and lipid-related diseases

Y Li, Z Ma, S Jiang, W Hu, T Li, S Di, D Wang… - Progress in lipid …, 2017 - Elsevier
Lipid metabolism is a complex physiological process that is involved in nutrient adjustment,
hormone regulation, and homeostasis. An unhealthy lifestyle and chronic nutrient overload …

PPARγ in immunity and inflammation: cell types and diseases

L Széles, D Töröcsik, L Nagy - … et Biophysica Acta (BBA)-Molecular and Cell …, 2007 - Elsevier
The lipid activated transcription factor, PPARγ appears to have multiple functions in the
immune system. There are several cell types expressing the receptor, most prominently …

Piperine, a component of black pepper, inhibits adipogenesis by antagonizing PPARγ activity in 3T3-L1 cells

UH Park, HS Jeong, EY Jo, T Park… - Journal of agricultural …, 2012 - ACS Publications
This study investigated the antiadipogenic activity of black pepper extract and its constituent
piperine in 3T3-L1 preadipocytes as well as the underlying molecular mechanisms. Both …