Current strategies for treatment of intervertebral disc degeneration: substitution and regeneration possibilities
Background Intervertebral disc degeneration has an annual worldwide socioeconomic
impact masked as low back pain of over 70 billion euros. This disease has a high …
impact masked as low back pain of over 70 billion euros. This disease has a high …
Deep learning-based high-accuracy quantitation for lumbar intervertebral disc degeneration from MRI
HD Zheng, YL Sun, DW Kong, MC Yin, J Chen… - Nature …, 2022 - nature.com
To help doctors and patients evaluate lumbar intervertebral disc degeneration (IVDD)
accurately and efficiently, we propose a segmentation network and a quantitation method for …
accurately and efficiently, we propose a segmentation network and a quantitation method for …
The association between pain scores and disc height change following discectomy surgery in lumbar disc herniation patients: a systematic review and meta-analysis
Purpose To evaluate the impact of discectomy on disc height (DH) in lumbar disc herniation
(LDH) patients following discectomy surgery and address the association of DH change with …
(LDH) patients following discectomy surgery and address the association of DH change with …
Local delivery of senolytic drug inhibits intervertebral disc degeneration and restores intervertebral disc structure
Intervertebral disc (IVD) degeneration (IVDD) is a leading cause of chronic low back pain.
There is a strong clinical demand for more effective treatments for IVDD as conventional …
There is a strong clinical demand for more effective treatments for IVDD as conventional …
Construction of biomimetic artificial intervertebral disc scaffold via 3D printing and electrospinning
M Zhu, J Tan, L Liu, J Tian, L Li, B Luo, C Zhou… - Materials Science and …, 2021 - Elsevier
Intervertebral disc (IVD) degeneration is a clinically disease that seriously endangers
people's health. Tissue engineering provides a promising method to repair and regenerate …
people's health. Tissue engineering provides a promising method to repair and regenerate …
The Pfirrmann classification of lumbar intervertebral disc degeneration: an independent inter-and intra-observer agreement assessment
Purpose Grading inter-vertebral disc degeneration (IDD) is important in the evaluation of
many degenerative conditions, including patients with low back pain. Magnetic resonance …
many degenerative conditions, including patients with low back pain. Magnetic resonance …
Long non-coding HCG18 promotes intervertebral disc degeneration by sponging miR-146a-5p and regulating TRAF6 expression
Y Xi, T Jiang, W Wang, J Yu, Y Wang, X Wu, Y He - Scientific reports, 2017 - nature.com
Intervertebral disc degeneration (IDD) is associated with the deterioration of nucleus
pulposus (NP) cells due to hypertrophic differentiation and calcification. Emerging studies …
pulposus (NP) cells due to hypertrophic differentiation and calcification. Emerging studies …
LncRNA OIP5-AS1 accelerates intervertebral disc degeneration by targeting miR-25-3p
Z Che, J Xueqin, Z Zhang - Bioengineered, 2021 - Taylor & Francis
It is obvious that epigenetic processes influence the evolution of intervertebral disc
degeneration (IDD). However, its molecular mechanisms are poorly understood. Long …
degeneration (IDD). However, its molecular mechanisms are poorly understood. Long …
Direct automated quantitative measurement of spine by cascade amplifier regression network with manifold regularization
S Pang, Z Su, S Leung, IB Nachum, B Chen… - Medical image …, 2019 - Elsevier
Automated quantitative measurement of the spine (ie, multiple indices estimation of heights,
widths, areas, and so on for the vertebral body and disc) plays a significant role in clinical …
widths, areas, and so on for the vertebral body and disc) plays a significant role in clinical …
Intervertebral disc classification by its degree of degeneration from T2-weighted magnetic resonance images
Purpose The primary goal of this article is to achieve an automatic and objective method to
compute the Pfirrmann's degeneration grade of intervertebral discs (IVD) from MRI. This …
compute the Pfirrmann's degeneration grade of intervertebral discs (IVD) from MRI. This …