Recent developments in a variety of sectors, including health care, research and the direct-
to-consumer industry, have led to a dramatic increase in the amount of genomic data that …

The global nephrology community recognises the need for a cohesive plan to address the
problem of chronic kidney disease (CKD). In July, 2016, the International Society of …

Abstract Background In 2021, the American College of Medical Genetics and Genomics
(ACMG) recommended reporting actionable genotypes in 73 genes associated with …

Personalized medicine has largely been enabled by the integration of genomic and other
data with electronic health records (EHRs) in the United States and elsewhere. Increased …

Clinical Next-Generation Sequencing—A Wild Frontier The technologies and chemistries
underlying next-generation sequencing of DNA are evolving rapidly. This review describes …

Genomic technologies are reaching the point of being able to detect genetic variation in
patients at high accuracy and reduced cost, offering the promise of fundamentally altering …

Advances in genotyping technology have, over the past decade, enabled the focused
search for common genetic variation associated with human diseases and traits. With the …

With the growth of precision medicine research on health data and biospecimens, research
institutions will need to build and maintain long-term, trusting relationships with patient …

Introduction Genetic data from the Alzheimer's Disease Neuroimaging Initiative (ADNI) have
been crucial in advancing the understanding of Alzheimer's disease (AD) pathophysiology …

Research with human subjects 1 exemplifies the perennial conflict between the good of the
individual and the good of society. Policies and procedures that protect the rights and …