Reporting specific modelling methods and metadata is essential to the reproducibility of
ecological studies, yet guidelines rarely exist regarding what information should be noted …

A substantial number of studies have reported the development of gene expression–based
prognostic signatures for lung cancer. The ultimate aim of such studies should be the …

It has been reported that angiotensin-converting enzyme 2 (ACE2) and transmembrane
serine protease 2 (TMPRSS2) are the main cell entry proteins for severe acute respiratory …

Previously undescribed prognostic subclasses of high-grade astrocytoma are identified and
discovered to resemble stages in neurogenesis. One tumor class displaying neuronal …

Apo2L/TRAIL stimulates cancer cell death through the proapoptotic receptors DR4 and DR5,
but the determinants of tumor susceptibility to this ligand are not fully defined. mRNA …

Abstract Protein kinase B (PKB/Akt) has been shown to play a role in protection from
apoptosis, cell proliferation and cell growth. It is also involved in mediating the effects of …

Significant improvements in the outcome of non–small cell lung carcinoma (NSCLC) have
been reported in patients treated with the epidermal growth factor receptor (EGFR) inhibitor …

Background Idiopathic pulmonary fibrosis (IPF) is an untreatable lung disease with a median
survival of only 3–5 years that is diagnosed using a combination of clinical, radiographic and …

Background Changes in dietary fat composition could lower the risk of developing metabolic
syndrome. Adipose tissue is an interesting tissue in this respect because of its role in lipid …

Facioscapulohumeral muscular dystrophy (FSHD) is an autosomal dominant disorder linked
to contractions of the D4Z4 repeat array in the subtelomeric region of chromosome 4q. By …