The Role of n-3 Polyunsaturated Fatty Acids in the Prevention and Treatment of Breast Cancer

J Liu, DWL Ma - nutrients, 2014 - mdpi.com
Breast cancer (BC) is the most common cancer among women worldwide. Dietary fatty
acids, especially n-3 polyunsaturated fatty acids (PUFA), are believed to play a role in …

Therapeutic potentials and modulatory mechanisms of fatty acids in bone

M Bao, K Zhang, Y Wei, W Hua, Y Gao, X Li… - Cell …, 2020 - Wiley Online Library
Bone metabolism is a lifelong process that includes bone formation and resorption.
Osteoblasts and osteoclasts are the predominant cell types associated with bone …

Growth-inhibitory effect of chitosan-coated liposomes encapsulating curcumin on MCF-7 breast cancer cells

M Hasan, K Elkhoury, N Belhaj, C Kahn, A Tamayol… - Marine drugs, 2020 - mdpi.com
Current anticancer drugs exhibit limited efficacy and initiate severe side effects. As such,
identifying bioactive anticancer agents that can surpass these limitations is a necessity. One …

Exosomes in bone remodeling and breast cancer bone metastasis

L Sadu, RH Krishnan, RL Akshaya, UR Das… - Progress in Biophysics …, 2022 - Elsevier
Exosomes are endosome-derived microvesicles that carry cell-specific biological cargo,
such as proteins, lipids, and noncoding RNAs (ncRNAs). They play a key role in bone …

NO-dependent vasodilation and deep tumor penetration for cascade-amplified antitumor performance

Q Xu, G Chen, G Chen, H Wu, Y Yang, Z Mai… - Journal of Controlled …, 2022 - Elsevier
Nonspecific biodistribution and poor permeability of conventional therapeutic agents in solid
tumors severely compromised the antitumor efficacy. Herein, we report a cascade tumor …

Omega‐3 fatty acids in pathological calcification and bone health

T Sharma, CC Mandal - Journal of food biochemistry, 2020 - Wiley Online Library
Abstract Omega‐3 fatty acids (ω‐3FAs) such as Docosahexaenoic acid (DHA) and
Eicosapentanoic acid (EPA), are active ingredient of fish oil, which have larger health …

Metformin and docosahexaenoic acid hybrid micelles for premetastatic niche modulation and tumor metastasis suppression

T Jiang, L Chen, Y Huang, J Wang, M Xu, S Zhou… - Nano Letters, 2019 - ACS Publications
Metastasis is the major cause of high mortality in cancer patients; thus, blocking the
metastatic process is of critical importance for cancer treatments. The premetastatic niche, a …

Long-chain omega-3 polyunsaturated fatty acids decrease mammary tumor growth, multiorgan metastasis and enhance survival

S Khadge, GM Thiele, JG Sharp, TR McGuire… - Clinical & Experimental …, 2018 - Springer
Epidemiological studies show a reduced risk of breast cancer (BC) in women consuming
high levels of long-chain (LC) omega-3 (ω-3) fatty acids (FAs) compared with women who …

[HTML][HTML] Docosahexaenoic acid (DHA), an omega-3 fatty acid, inhibits tumor growth and metastatic potential of ovarian cancer

L West, Y Yin, SR Pierce, Z Fang, Y Fan… - American journal of …, 2020 - ncbi.nlm.nih.gov
Omega-3 polyunsaturated fatty acids (PUFAs), such as those found in fish oil, are thought to
have anti-tumorigenic effects and may help to treat and prevent cancer, including ovarian …

Docosahexaenoic acid liposomes for targeting chronic inflammatory diseases and cancer: an in vitro assessment

A Alaarg, NY Jordan, JJF Verhoef… - International journal …, 2016 - Taylor & Francis
Inflammation, oxidative stress, and uncontrolled cell proliferation are common key features
of chronic inflammatory diseases, such as atherosclerosis and cancer. ω3 polyunsaturated …