Rheumatoid Arthritis-Associated Interstitial Lung Disease (RA-ILD): Update on Prevalence, Risk Factors, Pathogenesis, and Therapy

DI Sullivan, DP Ascherman - Current Rheumatology Reports, 2024 - Springer
Abstract Purpose of Review Rheumatoid arthritis is frequently complicated by interstitial lung
disease (RA-ILD), an underappreciated contributor to excess morbidity and mortality. The …

Modifiable risk factors linked to the development of rheumatoid arthritis: evidence, immunological mechanisms and prevention

JA Maisha, HS El-Gabalawy, LJ O'Neil - Frontiers in Immunology, 2023 - frontiersin.org
Rheumatoid Arthritis (RA) is a common autoimmune disease that targets the synovial joints
leading to arthritis. Although the etiology of RA remains largely unknown, it is clear that …

Rheumatoid arthritis: Pathophysiology, current therapeutic strategies and recent advances in targeted drug delivery system

R Deshmukh - Materials Today Communications, 2023 - Elsevier
Recent advancements in technology and science thoroughly changed the basic
understanding and treatment approach of rheumatoid arthritis (RA). RA is a chronic …

Genetic basis of defects in immune tolerance underlying the development of autoimmunity

AM Hocking, JH Buckner - Frontiers in Immunology, 2022 - frontiersin.org
Genetic variants associated with susceptibility to autoimmune disease have provided
important insight into the mechanisms responsible for the loss of immune tolerance and the …

Prevention of rheumatoid arthritis using a familial predictive medicine approach

P Ruscitti, M Nunziato, F Caso, R Scarpa… - Autoimmunity …, 2024 - Elsevier
Most of the chronic-degenerative diseases deserve a very early recognition of symptoms
and signs for the earliest secondary prevention, which could be also very useful in many …

Progression of pre-rheumatoid arthritis to clinical disease of joints: Potential role of mesenchymal stem cells

Y Sardana, GK Bhatti, C Singh, PK Sharma, PH Reddy… - Life Sciences, 2023 - Elsevier
Rheumatoid arthritis (RA) related autoimmunity is developed at mucosal sites due to the
interplay between genetic risk factors and environmental triggers. The pre-RA phase that …

A genome-wide association study for rheumatoid arthritis replicates previous HLA and non-HLA associations in a cohort from South Africa

EM Mathebula, D Sengupta, N Govind… - Human Molecular …, 2022 - academic.oup.com
The complex pathogenesis of rheumatoid arthritis (RA) is not fully understood, with few
studies exploring the genomic contribution to RA in patients from Africa. We report a genome …

The influences of perfluoroalkyl substances on the rheumatoid arthritis clinic

Y Zhao, H Jin, J Qu, S Zhang, S Hu, J Xue, M Zhao - BMC immunology, 2022 - Springer
Background The effect of environmental factors on genetically susceptible individuals is a
basic link in the pathogenesis of rheumatoid arthritis. Perfluoroalkyl substances (PFASs) are …

Peptidylarginine deiminase 2 gene polymorphisms in subjects with periodontitis predispose to rheumatoid arthritis

L Massarenti, C Enevold, D Damgaard… - International Journal of …, 2022 - mdpi.com
Epidemiologic studies have shown associations between periodontitis and rheumatoid
arthritis (RA), but a causal relationship has not been established. Citrullination of gingival …

[HTML][HTML] Autoantibodies against SUMO1-DHX35 in long-COVID

L Thurner, N Fadle, E Regitz, KD Preuss… - Journal of Translational …, 2022 - Elsevier
Long COVID is a collection of symptoms as a late sequelae of SARS-CoV-2 infection. It often
includes mental symptoms such as cognitive symptoms, persisting loss of smell and taste, in …