The human gastrointestinal tract (GI) harbors a diverse population of microbial life that
continually shapes host pathophysiological responses. Despite readily available abundant …

The intestinal mucosal barrier, also referred to as intestinal barrier, is widely recognized as a
critical player in gut homeostasis maintenance as it ensures the complex crosstalk between …

The intestinal epithelium has one of the highest rates of cellular turnover in a process that is
tightly regulated. As the transit-amplifying progenitors of the intestinal epithelium generate …

Pectins are dietary fibers with different structural characteristics. Specific pectin structures
can influence the gastrointestinal immune barrier by directly interacting with immune cells or …

The gastrointestinal (GI) tract represents a unique challenge to the mammalian immune
system. It must tolerate the presence of the luminal microbiota and thus not respond to their …

Nowadays, the oral use of probiotics is widespread. However, the safety profile with the use
of live probiotics is still a matter of debate. Main risks include: Cases of systemic infections …

The human gastrointestinal tract is colonized by trillions of microorganisms that interact with
the host to maintain structural and functional homeostasis. Acting as the interface between …

The immune system plays a critical role in shaping all facets of cancer, from the early
initiation stage through to metastatic disease and resistance to therapy. Our understanding …

Numerous studies have indicated that the progression of chronic kidney disease (CKD) to
end-stage renal disease (ESRD) is strictly associated with the accumulation of toxic …

Obesity and type 2 diabetes are associated with low-grade inflammation and specific
changes in gut microbiota composition,,,,,,. We previously demonstrated that administration …