Gallstone disease, obesity and the firmicutes/bacteroidetes ratio as a possible biomarker of gut dysbiosis

IN Grigor'eva - Journal of personalized medicine, 2020 - mdpi.com
Obesity is a major risk factor for developing gallstone disease (GSD). Previous studies have
shown that obesity is associated with an elevated Firmicutes/Bacteroidetes ratio in the gut …

Immunoglobulin A, an active liaison for host-microbiota homeostasis

AA Abokor, GH McDaniel, RM Golonka, C Campbell… - Microorganisms, 2021 - mdpi.com
Mucosal surfaces in the gastrointestinal tract are continually exposed to native, commensal
antigens and susceptible to foreign, infectious antigens. Immunoglobulin A (IgA) provides …

Gut microbiota causally affects cholelithiasis: a two-sample Mendelian randomization study

X Liu, X Qi, R Han, T Mao, Z Tian - Frontiers in cellular and infection …, 2023 - frontiersin.org
Background The gut microbiota is closely linked to cholesterol metabolism-related diseases
such as obesity and cardiovascular diseases. However, whether gut microbiota plays a …

Biliary diseases from the microbiome perspective: how microorganisms could change the approach to benign and malignant diseases

C Binda, G Gibiino, C Coluccio, M Sbrancia, E Dajti… - Microorganisms, 2022 - mdpi.com
Recent evidence regarding microbiota is modifying the cornerstones on pathogenesis and
the approaches to several gastrointestinal diseases, including biliary diseases. The burden …

Landscape in the gallbladder mycobiome and bacteriome of patients undergoing cholelithiasis with chronic cholecystitis

J Hu, J Tang, X Zhang, K Yang, A Zhong… - Frontiers in …, 2023 - frontiersin.org
Gallstone disease (GSD) is associated with changes in the gut and gallbladder bacterial
composition, but there is limited information on the role of the fungal community …

Gallstone disease and bacterial metabolic performance of gut microbiota in middle-aged and older patients

D Georgescu, I Ionita, A Lascu, EF Hut… - … Journal of General …, 2022 - Taylor & Francis
Background Gallstone disease (GSD) is more commonly presented in aged people.
Purpose The purpose of the study was to explore the insights of metabolic performance of …

Changes and correlations of the intestinal flora and liver metabolite profiles in mice with gallstones

Y Chen, Q Wang, W Gao, B Ma, D Xue… - Frontiers in Physiology, 2021 - frontiersin.org
There is increasing appreciation for the roles of the gut-liver axis in liver and gall diseases.
Specific gut microbes are associated with susceptibility to gallstone diseases, while the …

[HTML][HTML] Unveil intrahepatic cholangiocarcinoma heterogeneity through the lens of omics and multi-omics approaches

V Porreca, C Barbagallo, E Corbella, M Peres, M Stella… - Cancers, 2024 - mdpi.com
Simple Summary Intrahepatic cholangiocarcinoma (iCCA) is a highly aggressive primary
liver cancer leading to death in 10–15% of cases. In recent years, the iCCA worldwide …

Exploring Bile Acid Transporters As Key Players In Cancer Development And Treatment: Evidence From Preclinical And Clinical Studies

B Bintee, R Banerjee, M Hegde, R Vishwa… - Cancer Letters, 2024 - Elsevier
Bile acid transporters (BATs) are integral membrane proteins belonging to various families,
such as solute carriers, organic anion transporters, and ATP-binding cassette families …

A systematic review on omics data (metagenomics, metatranscriptomics, and metabolomics) in the role of microbiome in gallbladder disease

P Di Carlo, N Serra, R Alduina, R Guarino… - Frontiers in …, 2022 - frontiersin.org
Microbiotas are the range of microorganisms (mainly bacteria and fungi) colonizing
multicellular, macroscopic organisms. They are crucial for several metabolic functions …