Metabolic methanol: molecular pathways and physiological roles

YL Dorokhov, AV Shindyapina… - Physiological …, 2015 - journals.physiology.org
Methanol has been historically considered an exogenous product that leads only to
pathological changes in the human body when consumed. However, in normal, healthy …

Sulfide regulation of cardiovascular function in health and disease

GK Kolluru, RE Shackelford, X Shen… - Nature Reviews …, 2023 - nature.com
Hydrogen sulfide (H2S) has emerged as a gaseous signalling molecule with crucial
implications for cardiovascular health. H2S is involved in many biological functions …

Reactive Sulfur Species in human diseases

M Iciek, A Bilska-Wilkosz, M Kozdrowicki… - Antioxidants & Redox …, 2023 - liebertpub.com
Significance: Reactive sulfur species (RSS) have been recently recognized as redox
molecules no less important than reactive oxygen species or reactive nitrogen species. They …

Hydrogen Sulfide (H2S)-Releasing Compounds: Therapeutic Potential in Cardiovascular Diseases

L Zhang, Y Wang, Y Li, L Li, S Xu, X Feng… - Frontiers in …, 2018 - frontiersin.org
Cardiovascular disease is the main cause of death worldwide, but its pathogenesis is not yet
clear. Hydrogen sulfide (H2S) is considered to be the third most important endogenous …

[HTML][HTML] Alpha-lipoic acid treatment improves adverse cardiac remodelling in the diabetic heart–The role of cardiac hydrogen sulfide-synthesizing enzymes

GJ Dugbartey, QL Wonje, KK Alornyo, I Adams… - Biochemical …, 2022 - Elsevier
Introduction Alpha-lipoic acid (ALA) is a licensed drug for the treatment of diabetic
neuropathy. We recently reported that it also improves diabetic cardiomyopathy (DCM) in …

[HTML][HTML] Activation of renal CSE/H2S pathway by alpha-lipoic acid protects against histological and functional changes in the diabetic kidney

GJ Dugbartey, KK Alornyo, DE Diaba… - Biomedicine & …, 2022 - Elsevier
Introduction We previously reported that alpha-lipoic acid (ALA) supplementation protects
against progression of diabetic kidney disease (DKD). In this study, we aim to investigate …

Effects of Lipoic Acid on Ischemia‐Reperfusion Injury

Y Ding, Y Zhang, W Zhang, J Shang… - … medicine and cellular …, 2021 - Wiley Online Library
Ischemia‐reperfusion (I/R) injury often occurred in some pathologies and surgeries. I/R
injury not only harmed to physiological functions of corresponding organ and tissue but also …

Lipoic acid. Kinetics and pluripotent biological properties and derivatives

P Theodosis-Nobelos, G Papagiouvannis… - Molecular Biology …, 2021 - Springer
Lipoic acid (LA) is globally known and its supplements are widely used. Despite its
importance for the organism it is not considered a vitamin any more. The multiple metabolic …

The role of KATP channels in cerebral ischemic stroke and diabetes

V Szeto, N Chen, H Sun, Z Feng - Acta Pharmacologica Sinica, 2018 - nature.com
Abstract ATP-sensitive potassium (K ATP) channels are ubiquitously expressed on the
plasma membrane of cells in multiple organs, including the heart, pancreas and brain. K …

The protective effect of lipoic acid on selected cardiovascular diseases caused by age‐related oxidative stress

B Skibska, A Goraca - Oxidative Medicine and Cellular …, 2015 - Wiley Online Library
Oxidative stress is considered to be the primary cause of many cardiovascular diseases,
including endothelial dysfunction in atherosclerosis and ischemic heart disease …