Oxytocin: crossing the bridge between basic science and pharmacotherapy

C Viero, I Shibuya, N Kitamura… - CNS neuroscience & …, 2010 - Wiley Online Library
Is oxytocin the hormone of happiness? Probably not. However, this small nine amino acid
peptide is involved in a wide variety of physiological and pathological functions such as …

Oxytocin and pain: a systematic review and synthesis of findings

JA Rash, A Aguirre-Camacho… - The Clinical journal of …, 2014 - journals.lww.com
Objectives: A review of the literature was conducted to assess the association between
oxytocin (OT) and pain. Methods: PsychInfo, PubMed, and Medline (EBSCO) research …

[HTML][HTML] A new population of parvocellular oxytocin neurons controlling magnocellular neuron activity and inflammatory pain processing

M Eliava, M Melchior, HS Knobloch-Bollmann, J Wahis… - Neuron, 2016 - cell.com
Oxytocin (OT) is a neuropeptide elaborated by the hypothalamic paraventricular (PVN) and
supraoptic (SON) nuclei. Magnocellular OT neurons of these nuclei innervate numerous …

[图书][B] Brain arousal and information theory: neural and genetic mechanisms

DW Pfaff - 2006 - degruyter.com
Pfaff presents a daring perspective on the long-standing puzzle of what arousal is. He
argues that, beneath our mental functions and emotional dispositions, a primitive neuronal …

Molecular mechanisms of oxytocin signaling at the synaptic connection

J Bakos, A Srancikova, T Havranek… - Neural plasticity, 2018 - Wiley Online Library
Aberrant regulation of oxytocin signaling is associated with the etiology of
neurodevelopmental disorders. Synaptic dysfunctions in neurodevelopmental disorders are …

Oxytocin-induced analgesia and scratching are mediated by the vasopressin-1A receptor in the mouse

A Schorscher-Petcu, S Sotocinal, S Ciura… - Journal of …, 2010 - Soc Neuroscience
The neuropeptides oxytocin (OXT) and arginine vasopressin (AVP) contribute to the
regulation of diverse cognitive and physiological functions including nociception. Indeed …

Oxytocin-induced antinociception in the spinal cord is mediated by a subpopulation of glutamatergic neurons in lamina I-II which amplify GABAergic inhibition

JD Breton, P Veinante, S Uhl-Bronner… - Molecular …, 2008 - journals.sagepub.com
Background: Recent evidence suggests that oxytocin (OT), secreted in the superficial spinal
cord dorsal horn by descending axons of paraventricular hypothalamic nucleus (PVN) …

Oxytocin receptor signaling in the hippocampus: Role in regulating neuronal excitability, network oscillatory activity, synaptic plasticity and social memory

YT Lin, KS Hsu - Progress in neurobiology, 2018 - Elsevier
Beyond its well-known role in reproduction, the hypothalamic neuropeptide oxytocin (OXT)
has been implicated in a broad spectrum of social and nonsocial behaviors. The biological …

Oxytocin relieves neuropathic pain through GABA release and presynaptic TRPV1 inhibition in spinal cord

W Sun, Q Zhou, X Ba, X Feng, X Hu… - Frontiers in molecular …, 2018 - frontiersin.org
Objective: Oxytocin (OT) is synthesized within the paraventricular nucleus and supraoptic
nucleus of the hypothalamus. In addition to its role in uterine contraction, OT plays an …

The analgesic effects of oxytocin in the peripheral and central nervous system

Q Xin, B Bai, W Liu - Neurochemistry International, 2017 - Elsevier
Pain is a ubiquitously unpleasant feeling among humans as well as many animal species
often caused by actual and potential tissue damage. However, it is absolutely crucial for our …