Central nervous system (CNS) disorders affect as many as 1.5 billion people globally. The
limited delivery of most imaging and therapeutic agents into the brain is a major challenge …

Photodynamic therapy (PDT) and photothermal therapy (PTT) are photo-mediated
treatments with different mechanisms of action that can be addressed for cancer treatment …

Antifouling surfaces are important in a broad range of applications. An effective approach to
antifouling surfaces is to covalently attach antifouling polymer brushes. This work reports the …

Biofouling caused by nonspecific adsorption of biomolecules and organisms such as
proteins, cells, and bacteria to material surfaces is a significant challenge for numerous …

Minimizing the interaction of nanomedicines with the mononuclear phagocytic system (MPS)
is a critical challenge for their clinical translation. Conjugating polyethylene glycol (PEG) to …

The introduction of low-oxidation-state sulfur atoms is a popular strategy to provide
macromolecules with responsivity to oxidizing conditions, which in turn may confer them …

Over the last decade nanomaterials have had a major impact on human health for the early
detection and treatment of many diseases. The future success of clinically translatable …

This study addresses well-known shortcomings of poly (ethylene glycol)(PEG)-based
conjugates. PEGylation is by far the most common method employed to overcome …

Peritoneal metastasis (PM) is considered one of the most dreaded forms of cancer
metastases for both patients and physicians. Aggressive cytoreductive surgery (CRS) is the …

Non-thrombogenic surfaces for extracorporeal membrane oxygenation (ECMO) devices are
important to increase their duration of usage and to enable long-term life support. However …