Quantitation of dynamic total-body PET imaging: recent developments and future perspectives

F Gu, Q Wu - European Journal of Nuclear Medicine and Molecular …, 2023 - Springer
Background Positron emission tomography (PET) scanning is an important diagnostic
imaging technique used in disease diagnosis, therapy planning, treatment monitoring, and …

Quantitative rodent brain receptor imaging

K Herfert, JG Mannheim, L Kuebler, S Marciano… - Molecular Imaging and …, 2020 - Springer
Positron emission tomography (PET) is a non-invasive imaging technology employed to
describe metabolic, physiological, and biochemical processes in vivo. These include …

A unified framework for plasma data modeling in dynamic positron emission tomography studies

M Tonietto, G Rizzo, M Veronese… - IEEE Transactions …, 2018 - ieeexplore.ieee.org
Objective: Full quantification of dynamic positron emission tomography (PET) data requires
the knowledge of tracer concentration in the arterial plasma. However, its accurate …

Unveiling the biological side of PET-derived biomarkers: a simulation-based approach applied to PDAC assessment

L Cavinato, J Hong, M Wartenberg, S Reinhard… - European Journal of …, 2024 - Springer
Purpose Radiomics has revolutionized clinical research by enabling objective
measurements of imaging-derived biomarkers. However, the true potential of radiomics …

Dispersion-corrected extracorporeal arterial input functions in PET studies of mice: a comparison to intracorporeal microprobe measurements

J Cufe, F Gierse, KP Schäfers, S Hermann… - EJNMMI research, 2023 - Springer
Background Kinetic modelling of dynamic PET typically requires knowledge of the arterial
radiotracer concentration (arterial input function, AIF). Its accurate determination is very …

The ultra high sensitivity blood counter: a compact, MRI-compatible, radioactivity counter for pharmacokinetic studies in μl volumes

L Convert, O Sarrhini, M Paillé, N Salem… - Biomedical Physics …, 2022 - iopscience.iop.org
Quantification of physiological parameters in preclinical pharmacokinetic studies based on
nuclear imaging requires the monitoring of arterial radioactivity over time, known as the …

Continuous blood sampling in small animal positron emission tomography/computed tomography enables the measurement of the arterial input function

T Mann, J Kurth, A Möller, J Förster, B Vollmar… - JoVE (Journal of …, 2019 - jove.com
For quantitative analysis and bio-kinetic modeling of positron emission
tomography/computed tomography (PET/CT) data, the determination of the temporal blood …

Preclinical Experimentation in Neurology

K Herfert, S Marciano, L Kuebler, S Buss… - Radiopharmaceutical …, 2019 - Springer
The development of radiopharmaceuticals for positron emission tomography (PET) is an
emerging area of research in neuroscience that allows for the early and differential …

Feasibility of longitudinal brain pet with real-time arterial input function in rats

D Rey-Bretal, A Moscoso, N Gómez-Lado… - Molecular Imaging and …, 2021 - Springer
Purpose Preclinical dynamic brain PET studies remain hampered by the limitations related
to the measurement of the arterial input function (AIF). In this regard, the use of an arterial …

PET methodology in rat models of Parkinson's disease

A Schildt - 2020 - research.rug.nl
Parkinson's disease (PD) is one of the most common neurodegenerative diseases
worldwide. The use of animal, especially rodent, models is of utmost importance to expand …