Diabetes mellitus is an increasingly prevalent chronic metabolic disease characterized by
prolonged hyperglycemia that leads to long-term health consequences. It is estimated that …

Diabetic wound shows delayed and incomplete healing processes, which in turn exposes
patients to an environment with a high risk of infection. This article has summarized current …

Persistent hyper-inflammation is a distinguishing pathophysiological characteristic of chronic
wounds, and macrophage malfunction is considered as a major contributor thereof. In this …

The healing of cutaneous wounds is dependent on the progression through distinct, yet
overlapping phases of wound healing, including hemostasis, inflammation, proliferation, and …

Diabetic foot ulcers (DFUs) are one of the most common and serious complications of
diabetes mellitus, as wound healing is impaired in the diabetic foot. Wound healing is a …

Background Diabetic foot ulcers are serious and challenging wounds associated with high
risk of infection and lower-limb amputation. Ulcers are deemed neuroischaemic if peripheral …

Abstract Purpose of Review Diabetic foot ulcerations (DFU) affect 25% of patients with
diabetes mellitus during their lifetime and constitute a major health problem as they are often …

The anatomy and physiology of the microcirculation in human skin are complex. Normal
cutaneous microcirculation is organized in two parallel plexuses with capillary loops …

Diabetic foot ulcers (DFUs) are very important diabetes-related lesions that can lead to
serious physical consequences like amputations of limbs and equally severe social …

Chronic inflammation participates in the progression of multiple chronic diseases, including
obesity, diabetes mellitus (DM), and DM related complications. Diabetic ulcer, characterized …