Ionic liquids and organic salts with antimicrobial activity as a strategy against resistant microorganisms

FMS Costa, MLMFS Saraiva, MLC Passos - Journal of Molecular Liquids, 2022 - Elsevier
Antimicrobial resistance (AMR) is a subject of growing concern facing humanity caused
mainly by the overuse and misuse of antimicrobials, lack of adherence to antimicrobial …

A review of pyridine and pyrimidine derivatives as anti-MRSA agents

A Kumar, AK Singh, S Thareja, P Kumar - Anti-Infective Agents, 2023 - ingentaconnect.com
Background: Methicillin-resistant Staphylococcus aureus (MRSA) is a Gram-positive strain
whose resistance against existing antibiotics is a significant concern for researchers across …

The structure–activity correlation in the family of dicationic imidazolium surfactants: Antimicrobial properties and cytotoxic effect

AD Voloshina, SK Gumerova, АS Sapunova… - … et Biophysica Acta (BBA …, 2020 - Elsevier
Background The development of new effective microbicide surfactants and the search for the
structure–biological activity relationship is an important and promising problem. Surfactants …

Antimicrobial and cytotoxic effects of ammonium derivatives of diterpenoids steviol and isosteviol

AD Voloshina, AS Sapunova, NV Kulik… - Bioorganic & medicinal …, 2021 - Elsevier
Antimicrobial and cytotoxic activities of several ammonium derivatives of diterpenoids steviol
and isosteviol have been investigated in vitro. The results have showed that these …

Cationic imidazolium amphiphiles bearing a methoxyphenyl fragment: Synthesis, self-assembly behavior, and antimicrobial activity

DA Kuznetsova, DM Kuznetsov, SK Amerhanova… - Langmuir, 2022 - ACS Publications
Novel cationic amphiphiles of the 3-alkyl-1-(4-methoxyphenyl)-1 H-imidazol-3-ium bromide
series bearing methoxyphenyl fragments (MPI-n) have been synthesized. Their aggregation …

The wide-spectrum antimicrobial effect of novel N-alkyl monoquaternary ammonium salts and their mixtures; the QSAR study against bacteria

O Soukup, M Benkova, R Dolezal, R Sleha… - European journal of …, 2020 - Elsevier
Quaternary ammonium salts (QASs) have been widely used for disinfection purposes
because of their low price, high efficacy and low human toxicity for decades. However …

Synthesis, computational analyses, antibacterial and antibiofilm properties of nicotinamide derivatives

AHT Kafa, G Tüzün, E Güney, R Aslan, K Sayın… - Structural Chemistry, 2022 - Springer
Newly designed nicotinamide derivatives were synthesized and characterized using
spectral techniques (IR, 1H-NMR, 13C-NMR, and MS). Moreover, these compounds are …

Synthesis and in vitro evaluation of triphenylphosphonium derivatives of acetylsalicylic and salicylic acids: structure-dependent interactions with cancer cells, bacteria …

OV Tsepaeva, TI Salikhova, LR Grigor'eva… - Medicinal Chemistry …, 2021 - Springer
Salicylic acid (SA) remains one of the most fruitful natural compounds to generate drug
molecules with versatile activities. In this study, effective synthesis of SA and acetylsalicylic …

Recycling old antibiotics with ionic liquids

C Prudêncio, M Vieira, S Van der Auweraer, R Ferraz - Antibiotics, 2020 - mdpi.com
Antibiotics are considered one of the great “miracles” of the 20th century. Now in the 21st
century in the post-antibiotic era, the miracle is turning into a nightmare, due to the growing …

Present and Future Perspectives on Therapeutic Options for Carbapenemase-Producing Enterobacterales Infections

CO Vrancianu, EG Dobre, I Gheorghe, I Barbu… - Microorganisms, 2021 - mdpi.com
Carbapenem-resistant Enterobacterales (CRE) are included in the list of the most
threatening antibiotic resistance microorganisms, being responsible for often …