[HTML][HTML] Helminth extracellular vesicles: Interactions with the host immune system

C Drurey, RM Maizels - Molecular Immunology, 2021 - Elsevier
As long-lived parasites, helminths depend upon immunomodulation of their hosts for
survival. The release of excretory-secretory (ES) products, including proteins, lipids and …

Immunomodulation by helminths: intracellular pathways and extracellular vesicles

A Zakeri, EP Hansen, SD Andersen… - Frontiers in …, 2018 - frontiersin.org
Helminth parasites are masters at manipulating host immune responses, using an array of
sophisticated mechanisms. One of the major mechanisms enabling helminths to establish …

Helminth coinfection and COVID-19: an alternate hypothesis

R Hays, D Pierce, P Giacomin, A Loukas… - PLoS neglected …, 2020 - journals.plos.org
In their recently published commentary, Bradbury and colleagues [1] drew attention to the
possible negative interactions between helminth infection and COVID-19 severity in …

Fasciola hepatica-Derived Molecules as Regulators of the Host Immune Response

S Ryan, J Shiels, CC Taggart, JP Dalton… - Frontiers in …, 2020 - frontiersin.org
Helminths (worms) are one of the most successful organisms in nature given their ability to
infect millions of humans and animals worldwide. Their success can be attributed to their …

Obesity-mediated immune modulation: one step forward,(Th) 2 steps back

V Schmidt, AE Hogan, PG Fallon… - Frontiers in …, 2022 - frontiersin.org
Over the past decades, the relationship between the immune system and metabolism has
become a major research focus. In this arena of immunometabolism the capacity of adipose …

Potential influence of helminth molecules on COVID-19 pathology

M Siles-Lucas, J González-Miguel, R Geller… - Trends in …, 2021 - cell.com
In recent months, the parasitology research community has been tasked with investigation of
the influence of parasite coinfection on coronavirus disease 2019 (COVID-19) outcomes …

Schistosomes in the lung: immunobiology and opportunity

EL Houlder, AH Costain, PC Cook… - Frontiers in …, 2021 - frontiersin.org
Schistosome infection is a major cause of global morbidity, particularly in sub-Saharan
Africa. However, there is no effective vaccine for this major neglected tropical disease, and …

Host immunity and inflammation to pulmonary helminth infections

JE Weatherhead, P Gazzinelli-Guimaraes… - Frontiers in …, 2020 - frontiersin.org
Helminths, including nematodes, cestodes and trematodes, are complex parasitic organisms
that infect at least one billion people globally living in extreme poverty. Helminthic infections …

Equal rights for parasites: Windsor 1995, revisited after ecological parasitology has come of age

M Rubio-Godoy, GPP de León - Biological Conservation, 2023 - Elsevier
Lack of data to properly model key biological characteristics like abundance or distribution,
seriously hinder comprehension of biodiversity patterns and their drivers—even for …

Nebulized ivermectin for COVID-19 and other respiratory diseases, a proof of concept, dose-ranging study in rats

C Chaccour, G Abizanda, Á Irigoyen-Barrio… - Scientific reports, 2020 - nature.com
Ivermectin is a widely used antiparasitic drug with known efficacy against several single-
strain RNA viruses. Recent data shows significant reduction of SARS-CoV-2 replication in …