Plants in anticancer drug discovery: from molecular mechanism to chemoprevention

AJ Siddiqui, S Jahan, R Singh, J Saxena… - BioMed Research …, 2022 - Wiley Online Library
Cancer is one of the primary causes of mortality globally, and the discovery of new
anticancer drugs is the most important need in recent times. Natural products have been …

Strategies and lessons learned from total synthesis of taxol

L Min, JC Han, W Zhang, CC Gu, YP Zou… - Chemical …, 2023 - ACS Publications
Taxol (paclitaxel), the most well-known taxane diterpenoid, is the best-selling natural-source
anticancer drug ever produced and one of the most common prescriptions in the treatment of …

Molecules from nature: Reconciling biodiversity conservation and global healthcare imperatives for sustainable use of medicinal plants and fungi

MJR Howes, CL Quave, J Collemare… - Plants, People …, 2020 - Wiley Online Library
Societal Impact Statement Plants and fungi have provided, or inspired, key pharmaceuticals
for global health challenges, including cancer, heart disease, dementia, and malaria, and …

Elicitation, an effective strategy for the biotechnological production of bioactive high-added value compounds in plant cell factories

K Ramirez-Estrada, H Vidal-Limon, D Hidalgo… - Molecules, 2016 - mdpi.com
Plant in vitro cultures represent an attractive and cost-effective alternative to classical
approaches to plant secondary metabolite (PSM) production (the “Plant Cell Factory” …

Biosynthesis of nanoparticles using plant extracts and essential oils

S Antunes Filho, MS Dos Santos, OAL Dos Santos… - Molecules, 2023 - mdpi.com
Plant extracts and essential oils have a wide variety of molecules with potential application
in different fields such as medicine, the food industry, and cosmetics. Furthermore, these …

Plants as sources of natural and recombinant anti-cancer agents

JF Buyel - Biotechnology advances, 2018 - Elsevier
Herbal remedies were the first medicines used by humans due to the many
pharmacologically active secondary metabolites produced by plants. Some of these …

SuperNatural 3.0—a database of natural products and natural product-based derivatives

K Gallo, E Kemmler, A Goede, F Becker… - Nucleic Acids …, 2023 - academic.oup.com
Natural products (NPs) are single chemical compounds, substances or mixtures produced
by a living organism-found in nature. Evolutionarily, NPs have been used as healing agents …

Production of the anticancer drug taxol in Taxus baccata suspension cultures: a review

S Malik, RM Cusidó, MH Mirjalili, E Moyano… - Process …, 2011 - Elsevier
Plant cell factories constitute an alternative source of high added value phytochemicals such
as the anticancer drug taxol (generic name paclitaxel), biosynthesized in Taxus spp. The …

[图书][B] Anticancer agents from natural products

GM Cragg, DGI Kingston, DJ Newman - 2005 - taylorfrancis.com
Plants, marine organisms, and microorganisms have evolved complex chemical defense
and signaling systems that are designed to protect them from predators and provide other …

Current development of cabazitaxel drug delivery systems

B Sun, JF Lovell, Y Zhang - Wiley Interdisciplinary Reviews …, 2023 - Wiley Online Library
The second‐generation taxane cabazitaxel has been clinically approved for the treatment of
metastatic castration‐resistant prostate cancer after docetaxel failure. Compared with the …