Homocysteine (Hcy), a sulfur amino acid, is the only direct precursor for l-methionine
synthesis through a reaction that requires vitamin B12, representing a connection with “one …

Recent years, it is a highly debated topic that whether methylenetetrahydrofolate reductase
(MTHFR) C677T polymorphism and A1298C polymorphism could increase susceptibility to …

Background Venous thromboembolism (VTE) could be manifested as deep venous
thrombosis (DVT) or pulmonary embolism (PE). DVT is usually the more common …

Background Genetic risk factors play an important role in the pathogenesis of Alzheimer's
disease (AD). In this case-control study, we examined the C677T and A1298C …

Background Thrombophilia is a substantial source of indisposition and mortality in several
countries, including Arab populations. Deep venous thrombosis (DVT) with or without …

Cerebral venous thrombosis (CVT) is a rare but devastating complication of inflammatory
bowel disease (IBD). Here we describe six IBD patients with cerebral venous thrombosis …

Aim: To determine the concentration of total plasma homocysteine (tHcy) as well as different
genotypes of methylenetetrahydrofolate reductase MTHFR (C677T) in healthy subjects and …

Hyperhomocysteinemia known to be associated with increased thrombotic tendency has
been considered as a risk factor for coronary artery disease, atherosclerosis, venous …

Aim The aim of this study is to determine the association between C677T polymorphism in
MTHFR gene and plasma homocysteine concentration in recurrent fetal miscarriages …

BACKGROUND: Acute first-ever ischemic stroke (FIS) is a heterogeneous, polygenic
disorder. The contribution of vascular genetic variants as inherited causes of ischemic stroke …