How to translate DNA methylation biomarkers into clinical practice

W Wagner - Frontiers in Cell and Developmental Biology, 2022 - frontiersin.org
Recent advances in sequencing technologies provide unprecedented opportunities for
epigenetic biomarker development. Particularly the DNA methylation pattern—which is …

Longitudinal study of DNA methylation and epigenetic clocks prior to and following test-confirmed COVID-19 and mRNA vaccination

APS Pang, AT Higgins-Chen, F Comite, I Raica… - Frontiers in …, 2022 - frontiersin.org
The host epigenetic landscape rapidly changes during SARS-CoV-2 infection, and evidence
suggest that severe COVID-19 is associated with durable scars to the epigenome …

Development of epigenetic biomarkers in aquatic organisms

D Anastasiadi, A Beemelmanns - Epigenetics in aquaculture, 2023 - Wiley Online Library
Biomarkers, as measurable characteristics of normal or pathogenic processes, are used in
the context of human health and to monitor animal welfare and ecosystem status. Epigenetic …

Novel feature selection methods for construction of accurate epigenetic clocks

A Li, A Mueller, B English, A Arena, D Vera… - PLoS Computational …, 2022 - journals.plos.org
Epigenetic clocks allow us to accurately predict the age and future health of individuals
based on the methylation status of specific CpG sites in the genome and are a powerful tool …

Analytical Methods and Tools to Study the Epigenome

O Ortega‐Recalde, TA Hore - Epigenetics in Aquaculture, 2023 - Wiley Online Library
Advances in multiple disciplines such as genetics, molecular biology, and organismal
biology have highlighted the importance of epigenetic marks in gene regulation …

Tracking single cell evolution via clock-like chromatin accessibility

Y Xiao, W Jin, L Ju, J Fu, G Wang, M Yu, F Chen… - bioRxiv, 2022 - biorxiv.org
Single cell chromatin accessibility sequencing (scATAC) reconstructs developmental
trajectory by phenotypic similarity. However, inferring the exact developmental trajectory is …

Epigenetics in aquaculture: knowledge gaps, challenges, and future prospects

F Piferrer - Epigenetics in Aquaculture, 2023 - Wiley Online Library
This chapter provides some additional thoughts, points out knowledge gaps that need to be
addressed, attempts to identify overall challenges that must be overcome, and outlines some …

Wearable-ome meets epigenome: A novel approach to measuring biological age with wearable devices

C Sugden, FB du Preez, LR Olivier, A Deffur - bioRxiv, 2023 - biorxiv.org
Aging is an inevitable process of cellular and physiological decline. These markers of age
can be measured on the molecular and functional level. Wearable devices offer a non …