Despite the decline in death rate from breast cancer and recent advances in targeted
therapies and combinations for the treatment of metastatic disease, metastatic breast cancer …

Epithelial–mesenchymal transition or EMT is an extremely dynamic process involved in
conversion of epithelial cells into mesenchymal cells, stimulated by an ensemble of …

The transcription factor family activator protein 2 (TFAP2) is vital for regulating both
embryonic and oncogenic development. The TFAP2 family consists of five DNA-binding …

Colorectal cancer stem cells (CSCs) have the potential for self-renewal, proliferation, and
differentiation. And LGR5 is a stem cell marker gene of colorectal cancer. Curcumin can …

Arrhythmogenic cardiomyopathy (ACM) is an inherited disorder often caused by pathogenic
variants in desmosomal genes and characterized by progressive fibrotic and fat tissue …

Objectives: keratin 16 (KRT16) is a type I cytokeratin that overexpressed in many kinds of
cancers, but unlike other keratins, KRT16 was poorly studied, so the aim of current study …

The dynamic synergy of genes and pathways in muscles in relation to age affects the muscle
characteristics. Investigating the temporal changes in gene expression will help illustrate the …

Renal fibrosis represents a key pathophysiological process in patients with chronic kidney
diseases (CKD) and is typically associated with a poor prognosis. Renal tubular epithelial …

Epithelial to mesenchymal transition (EMT) is a well-studied hallmark of epithelial-like
cancers that is characterized by loss of epithelial markers and gain of mesenchymal …

Background: Breast cancer is still a leading threat to women's lives. Long non-coding RNAs
(lncRNA) associated with cancer progression are getting attention. The objective of this …