Bispecific antibody use in patients with lymphoma and multiple myeloma

A Braun, S Gouni, A Pulles, P Strati… - American Society of …, 2024 - ascopubs.org
This article endeavors to navigate the clinical journey of bispecific antibodies (BsAbs), from
elucidating common toxicities and management strategies to examining novel agents and …

[HTML][HTML] Safety and Efficacy of Bispecific Antibodies in Adults with Large B-Cell Lymphomas: A Systematic Review of Clinical Trial Data

E Bayly-McCredie, M Treisman, S Fiorenza - International Journal of …, 2024 - mdpi.com
Bispecific antibodies (bsAbs) are an emerging therapy in the treatment of large B-cell
lymphomas (LBCLs). There is a gap in the research on the safety and efficacy of bsAbs in …

Bioengineering chitosan–antibody/fluorescent quantum dot nanoconjugates for targeted immunotheranostics of non-hodgkin B-cell lymphomas

SM Carvalho, AAP Mansur, ZIP Lobato, MF Leite… - International Journal of …, 2025 - Elsevier
B-cell non-Hodgkin lymphoma (NHL) is the most common hematologic malignancy, capable
of invading the brain, meninges, and nerve roots of the brain and spine, leading to high …

Bromodomain proteins as potential therapeutic targets for B-cell non-Hodgkin lymphoma

D Zou, S Feng, B Hu, M Guo, Y Lv, R Ma, Y Du, J Feng - Cell & Bioscience, 2024 - Springer
Background B-cell non-Hodgkin lymphoma (B-NHL) is the most common type of lymphoma
and is significantly heterogeneous among various subtypes. Despite of considerable …

[HTML][HTML] Bispecific Antibodies for Lymphoid Malignancy Treatment

M Bisio, L Legato, F Fasano, C Benevolo Savelli… - Cancers, 2024 - mdpi.com
Backgroud: The introduction of highly active immunotherapies has changed the outcome of
B-cell non-Hodgkin lymphomas (B-NHLs) in the last two decades. Since then, important …

Looking ahead to CD3, T-cell engager bispecific antibodies for hematological malignancies

DR Reed, LG Lum - Expert Opinion on Biological Therapy, 2024 - Taylor & Francis
Introduction Since the approval of the bispecific antibody blinatumomab in 2017 for the
treatment of acute lymphoblastic leukemia in relapse, the development of numerous …

[HTML][HTML] Antibody-Based Immunotherapies for the Treatment of Hematologic Malignancies

J Jureczek, K Kałwak, P Dzięgiel - Cancers, 2024 - mdpi.com
Despite the great advancements in treatment strategies for hematological malignancies
(HMs) over the years, their effective treatment remains challenging. Conventional treatment …

The causality between gut microbiota and non-Hodgkin lymphoma: a two-sample bidirectional Mendelian randomization study

J Fu, Z Hao - Frontiers in Microbiology, 2024 - frontiersin.org
Background Studies have indicated an association between gut microbiota (GM) and non-
Hodgkin lymphoma (NHL). However, the causality between GM and NHL remains unclear …

[HTML][HTML] Tumor Biology Hides Novel Therapeutic Approaches to Diffuse Large B-Cell Lymphoma: A Narrative Review

R Masnikosa, Z Cvetković, D Pirić - International Journal of Molecular …, 2024 - mdpi.com
Diffuse large B-cell lymphoma (DLBCL) is a malignancy of immense biological and clinical
heterogeneity. Based on the transcriptomic or genomic approach, several different …

Desensitization Strategies for Donor-Specific Antibodies in HLA-Mismatched Stem Cell Transplantation Recipients: What We Know and What We Do Not Know

Y Zhou, YL Chen, XY Huang, YJ Chang - Oncology and Therapy, 2024 - Springer
In human leukocyte antigen (HLA)-mismatched allogeneic stem cell transplantation settings,
donor-specific anti-HLA antibodies (DSAs) can independently lead to graft failure, including …