NEURONAL SUBSTRATES OF COMPLEX BEHAVIORS IN C. ELEGANS

M Bono, A Villu Maricq - Annu. Rev. Neurosci., 2005 - annualreviews.org
A current challenge in neuroscience is to bridge the gaps between genes, proteins, neurons,
neural circuits, and behavior in a single animal model. The nematode Caenorhabditis …

Function of RNA-binding protein Musashi-1 in stem cells

H Okano, H Kawahara, M Toriya, K Nakao… - Experimental cell …, 2005 - Elsevier
Musashi is an evolutionarily conserved family of RNA-binding proteins that is preferentially
expressed in the nervous system. The first member of the Musashi family was identified in …

Whole-Genome Shotgun Assembly and Analysis of the Genome of Fugu rubripes

S Aparicio, J Chapman, E Stupka, N Putnam, J Chia… - Science, 2002 - science.org
The compact genome of Fugu rubripes has been sequenced to over 95% coverage, and
more than 80% of the assembly is in multigene-sized scaffolds. In this 365-megabase …

Genome analysis: RNA recognition motif (RRM) and K homology (KH) domain RNA-binding proteins from the flowering plant Arabidopsis thaliana

ZJ Lorković, A Barta - Nucleic acids research, 2002 - academic.oup.com
Regulation of gene expression at the post-transcriptional level is mainly achieved by
proteins containing well-defined sequence motifs involved in RNA binding. The most widely …

Musashi: a translational regulator of cell fate

H Okano, T Imai, M Okabe - Journal of cell science, 2002 - journals.biologists.com
Transcription is thought to have a major role in the regulation of cell fate; the importance of
translational regulation in this process has been less certain. Recent findings demonstrate …

Rna-binding protein Musashi2: developmentally regulated expression in neural precursor cells and subpopulations of neurons in mammalian CNS

S Sakakibara, Y Nakamura, H Satoh… - Journal of …, 2001 - Soc Neuroscience
Musashi1 (Msi1) is a mammalian neural RNA-binding protein highly enriched in neural
precursor cells that are capable of generating both neurons and glia during embryonic and …

Musashi signaling in stem cells and cancer

RG Fox, FD Park, CS Koechlein… - Annual review of cell …, 2015 - annualreviews.org
How a single cell gives rise to an entire organism is one of biology's greatest mysteries.
Within this process, stem cells play a key role by serving as seed cells capable of both self …

[HTML][HTML] Forgetting is regulated via Musashi-mediated translational control of the Arp2/3 complex

N Hadziselimovic, V Vukojevic, F Peter, A Milnik… - Cell, 2014 - cell.com
A plastic nervous system requires the ability not only to acquire and store but also to forget.
Here, we report that musashi (msi-1) is necessary for time-dependent memory loss in C …

Structure of Musashi1 in a complex with target RNA: the role of aromatic stacking interactions

T Ohyama, T Nagata, K Tsuda… - Nucleic acids …, 2012 - academic.oup.com
Abstract Mammalian Musashi1 (Msi1) is an RNA-binding protein that regulates the
translation of target mRNAs, and participates in the maintenance of cell 'stemness' and …

A conserved three-nucleotide core motif defines Musashi RNA binding specificity

NR Zearfoss, LM Deveau, CC Clingman… - Journal of Biological …, 2014 - ASBMB
Musashi (MSI) family proteins control cell proliferation and differentiation in many biological
systems. They are overexpressed in tumors of several origins, and their expression level …