With reference to reference genes: a systematic review of endogenous controls in gene expression studies

JR Chapman, J Waldenström - PloS one, 2015 - journals.plos.org
The choice of reference genes that are stably expressed amongst treatment groups is a
crucial step in real-time quantitative PCR gene expression studies. Recent guidelines have …

Time-course effects of acute aflatoxin B1 exposure on hepatic mitochondrial lipids and oxidative stress in rats

OA Rotimi, SO Rotimi, JM Goodrich… - Frontiers in …, 2019 - frontiersin.org
Aflatoxins are secondary metabolites of certain Aspergillus species, that contaminate staple
foods, particularly in developing countries. Aflatoxin B1 (AFB1) is the most toxic and …

Mechanisms and measurement of changes in gene expression

KP Singh, C Miaskowski, AA Dhruva… - … research for nursing, 2018 - journals.sagepub.com
Research on gene expression (GE) provides insights into the physiology of a cell or group of
cells at a given point in time. Studies of changes in GE can be used to identify patients at …

[HTML][HTML] Changes and significance of SYP and GAP-43 expression in the hippocampus of CIH rats

X Zhu, P Wang, H Liu, J Zhan, J Wang… - … journal of medical …, 2019 - ncbi.nlm.nih.gov
Synaptophysin (SYP) and growth-associated binding protein 43 (GAP-43) have been shown
to be closely related to hippocampal synaptic plasticity in recent years. They are important …

A systematic review on the selection of reference genes for gene expression studies in rodents: are the classics the best choice?

TT Bunde, ACK Pedra, NR de Oliveira… - Molecular Biology …, 2024 - Springer
Rodents are commonly used as animal models in studies investigating various experimental
conditions, often requiring gene expression analysis. Quantitative real-time reverse …

Activation of inflammasomes and their effects on neuroinflammation at the microelectrode-tissue interface in intracortical implants

ME Franklin, C Bennett, M Arboite, A Alvarez-Ciara… - Biomaterials, 2023 - Elsevier
Invasive neuroprosthetics rely on microelectrodes (MEs) to record or stimulate the activity of
large neuron assemblies. However, MEs are subjected to tissue reactivity in the central …

Neurobehavioral effects of restricted and unpredictable environmental enrichment in rats

M Rojas-Carvajal, A Sequeira-Cordero… - Frontiers in …, 2020 - frontiersin.org
To study how motivational factors modulate experience-dependent neurobehavioral
plasticity, we modify a protocol of environmental enrichment (EE) in rats. We assumed that …

Cardioprotective antioxidant and anti-inflammatory mechanisms induced by intermittent hypobaric hypoxia

A González-Candia, AA Candia, A Paz, F Mobarec… - Antioxidants, 2022 - mdpi.com
More than 80 million people live and work (in a chronic or intermittent form) above 2500
masl, and 35 million live in the Andean Mountains. Furthermore, in Chile, it is estimated that …

Agave salmiana fructans as gut health promoters: Prebiotic activity and inflammatory response in Wistar healthy rats

AIC Andrade, CR Bautista, MAR Cabrera… - International journal of …, 2019 - Elsevier
Prebiotic effects of Agave salmiana fructans at five different doses were evaluated by the
growth of Bifidobacterium, Lactobacillus, and Clostridium strains and SCFA production in the …

Altered sialin mRNA gene expression in type 2 diabetic male Wistar rats: implications for nitric oxide deficiency

N Yousefzadeh, S Jeddi, M Zarkesh, K Kashfi… - Scientific Reports, 2023 - nature.com
Nitrate therapy has been suggested to boost nitric oxide (NO) levels in type 2 diabetes
(T2D); however, little is known about nitrate transport across the membranes. This study …