Prospects for combined use of oncolytic viruses and CAR T-cells
A Ajina, J Maher - Journal for immunotherapy of cancer, 2017 - Springer
With the approval of talimogene laherparepvec (T-VEC) for inoperable locally advanced or
metastatic malignant melanoma in the USA and Europe, oncolytic virotherapy is now …
metastatic malignant melanoma in the USA and Europe, oncolytic virotherapy is now …
The in silico human surfaceome
D Bausch-Fluck, U Goldmann… - Proceedings of the …, 2018 - National Acad Sciences
Cell-surface proteins are of great biomedical importance, as demonstrated by the fact that
66% of approved human drugs listed in the DrugBank database target a cell-surface protein …
66% of approved human drugs listed in the DrugBank database target a cell-surface protein …
The Cancer Surfaceome Atlas integrates genomic, functional and drug response data to identify actionable targets
Cell-surface proteins (SPs) are a rich source of immune and targeted therapies. By
systematically integrating single-cell and bulk genomics, functional studies and target …
systematically integrating single-cell and bulk genomics, functional studies and target …
A human IgSF cell-surface interactome reveals a complex network of protein-protein interactions
Cell-surface protein-protein interactions (PPIs) mediate cell-cell communication, recognition,
and responses. We executed an interactome screen of 564 human cell-surface and secreted …
and responses. We executed an interactome screen of 564 human cell-surface and secreted …
Cellinker: a platform of ligand–receptor interactions for intercellular communication analysis
Abstract Motivation Ligand–receptor (L–R) interactions mediate cell adhesion, recognition
and communication and play essential roles in physiological and pathological signaling …
and communication and play essential roles in physiological and pathological signaling …
[HTML][HTML] Genome-wide identification of cancer/testis genes and their association with prognosis in a pan-cancer analysis
VL da Silva, AF Fonseca, M Fonseca, TE da Silva… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Cancer/testis (CT) genes are excellent candidates for cancer immunotherapies because of
their restrict expression in normal tissues and the capacity to elicit an immune response …
their restrict expression in normal tissues and the capacity to elicit an immune response …
Surfaceome profiling suggests potential of anti-MUC1× EGFR bispecific antibody for breast cancer targeted therapy
Breast cancer (BC) treatment has traditionally been challenging due to tumor heterogeneity.
Bispecific antibodies (bsAbs) offer a promising approach for overcoming these challenges …
Bispecific antibodies (bsAbs) offer a promising approach for overcoming these challenges …
An Assessment of the Penile Squamous Cell Carcinoma Surfaceome for Biomarker and Therapeutic Target Discovery
Simple Summary Penile cancer is considered a rare disease in most developed countries,
yet it represents a significant global oncology challenge. Many patients are faced with …
yet it represents a significant global oncology challenge. Many patients are faced with …
Identification of key genes and prognostic value analysis in hepatocellular carcinoma by integrated bioinformatics analysis
M Wang, L Wang, S Wu, D Zhou… - International journal of …, 2019 - Wiley Online Library
Emerging evidence indicates that various functional genes with altered expression are
involved in the tumor progression of human cancers. This study is aimed at identifying novel …
involved in the tumor progression of human cancers. This study is aimed at identifying novel …
Data-driven identification of targets for fluorescence-guided surgery in non-small cell lung cancer
RPJ Meijer, LKA Neijenhuis, AP Zeilstra… - Molecular Imaging and …, 2023 - Springer
Purpose Intraoperative identification of lung tumors can be challenging. Tumor-targeted
fluorescence-guided surgery can provide surgeons with a tool for real-time intraoperative …
fluorescence-guided surgery can provide surgeons with a tool for real-time intraoperative …