Tissues such as the intestine harbor stem cells that have remarkable functional plasticity in
response to a dynamic environment. To adapt to the environment, stem cells constantly …

Autophagy is an important process that maintains adult tissue homeostasis and functions by
protecting cells in autonomous and non-cell-autonomous ways. By degrading toxic …

Interactions between prokaryotes and eukaryotes require a dialogue between MAMPs and
PRRs. In Drosophila, bacterial peptidoglycan is detected by PGRP receptors. While the …

Background: Crohn's disease (CD) is characterized by intestinal inflammation. Diet is a risk
factor for inflammatory bowel diseases such as CD and represents a promising adjunctive …

Endosomes are characterized by the presence of various phosphoinositides that are
essential for defining the membrane properties. However, the interplay between endosomal …

Scope Colonic mucosal healing is the terminal goal for the treatment of ulcerative colitis
(UC), but there is currently no specific drug available. This study investigates the beneficial …

Because the intestinal epithelium faces many stresses, dysregulation of essential
mechanisms governing gut homeostasis, such as autophagy, has been associated with …

Tato bakalářská práce je zaměřena na proces regenerace epitelu gastrointestinálního
traktu. V práci je popsána anatomická a buněčná stavba gastrointestinálního traktu …

Le trafic membranaire est un processus essentiel afin de réguler les fonctions et la survie
des cellules en permettant le transport des divers cargos vers leurs compartiments cibles …

Some of the interactions between prokaryotes and eukaryotes are mediated by a molecular
dialogue between microbial MAMPs and host PRRs. Bacteria-derived peptidoglycan, which …