A review of the mechanisms of action of dimethylfumarate in the treatment of psoriasis

J Brück, R Dringen, A Amasuno… - Experimental …, 2018 - Wiley Online Library
Fumaric acid esters (FAEs) such as dimethylfumarate (DMF) are used for the treatment of
adults with moderate‐to‐severe psoriasis. The mode of action of FAEs is complex. Here, we …

IL-12 and IL-23—close relatives with structural homologies but distinct immunological functions

DM Floss, JM Moll, J Scheller - Cells, 2020 - mdpi.com
Cytokines of the IL-12 family show structural similarities but have distinct functions in the
immune system. Prominent members of this cytokine family are the pro-inflammatory …

Food, gut barrier dysfunction, and related diseases: A new target for future individualized disease prevention and management

L Liang, C Saunders, N Sanossian - Food Science & Nutrition, 2023 - Wiley Online Library
Dysfunction of gut barrier is known as “leaky gut” or increased intestinal permeability.
Numerous recent scientific evidences showed the association between gut dysfunction and …

A possible role of intestinal microbiota in the pathogenesis of ankylosing spondylitis

L Yang, L Wang, X Wang, CJ Xian, H Lu - International journal of …, 2016 - mdpi.com
Ankylosing spondylitis (AS) is a chronic inflammatory disease primarily affecting the
sacroiliac joints and the spine, for which the pathogenesis is thought to be a result of the …

Regeneration and repair in the healing lung

A Lucas, J Yasa, M Lucas - Clinical & Translational …, 2020 - Wiley Online Library
The lung achieves an efficient gas exchange between a complex non‐sterile atmosphere
and the body via a delicate and extensive epithelial surface, with high efficiency because of …

Impact of Th-17 cytokines on the regulation of transporters in human placental explants

K Mirdamadi, J Kwok, O Nevo, H Berger… - Pharmaceutics, 2021 - mdpi.com
Activated T helper 17 (Th-17) cytokines play a role in the pathophysiology of autoimmune
and infectious diseases. While these diseases affect many women of childbearing age, little …

TSLP protects corneas from Pseudomonas aeruginosa infection by regulating dendritic cells and IL-23-IL-17 pathway

X Cui, N Gao, R Me, J Xu… - … Ophthalmology & Visual …, 2018 - iovs.arvojournals.org
Purpose: We sought to determine the role of epithelium-produced thymic stromal
lymphopoietin (TSLP) and its underlying mechanisms in corneal innate immune defense …

The role of memory T cells in Echinococcus granulosus‐induced sensitization

JR Zhou, XX Du, X Abulajiang, W Geli… - Immunity …, 2023 - Wiley Online Library
Objective To investigate the changes in memory T cells and the related factors in mice by the
establishment of a BALB/c mouse model of Echinococcus granulosus‐induced sensitization …

Protein-protein interactions: a structural view of inhibition strategies and the IL-23/IL-17 axis

SJ Allen, KJ Lumb - Advances in protein chemistry and structural biology, 2020 - Elsevier
Protein-protein interactions are central to biology and provide opportunities to modulate
disease with small-molecule or protein therapeutics. Recent developments in the …

[PDF][PDF] Volatile Organic Compounds (VOCs) and Interleukin-23 Levels in Lung Cancer: A Future Biomarker

RDW Listiandoko, UA Setyawan, TW Astuti… - 2022 - academia.edu
Introduction: Lung cancer (LC) is the world's second leading cause of death due to
malignancy. In Indonesia, LC is one of the top three malignancies. Volatile organic …