The lipid bilayer component of biological membranes is important for the distribution,
organization, and function of bilayer-spanning proteins. This regulation is due to both …

The simplest cell-like structure, the lipid bilayer vesicle, can respond to mechanical
deformation by elastic membrane dilation/thinning and curvature changes. When a protein is …

The condensing effect of cholesterol on phospholipid bilayers was systematically
investigated for saturated and unsaturated chains, as a function of cholesterol concentration …

Recent research has provided an abundance of new information on membrane
biochemistry. Now more than ever, it is essential to update our current understanding of …

The linear peptide gramicidin forms prototypical ion channels specific for monovalent
cations and has been extensively used to study the organization, dynamics and function of …

Membrane protein function is regulated by the host lipid bilayer composition. This regulation
may depend on specific chemical interactions between proteins and individual molecules in …

The deformation free energy of a lipid bilayer is presented based on the principle of a
continuum theory. For small deformations, the free energy consists of a layer-compression …

The function of membrane proteins often depends on the proteins' interaction with their lipid
environment, spectacularly so in the case of mechanosensitive channels, which are gated …

Antimicrobial peptides are known to form pores in cell membranes. We study this process in
model bilayers of various lipid compositions. We use two of the best-studied peptides …

VDAC is the major permeability pathway in the mitochondrial outer membrane and can
control the flow of metabolites and ions. Therefore Ca2+ flux across the outer membrane …