The extracellular matrix (ECM) is a ubiquitous member of the body and is key to the
maintenance of tissue and organ integrity. Initially thought to be a bystander in many cellular …

Collagens serve essential mechanical functions throughout the body, particularly in the
connective tissues. In articular cartilage, collagens provide most of the biomechanical …

Renal fibrosis is a common pathway toward chronic kidney disease (CKD) and is the main
pathological predecessor for end-stage renal disease; thus, preventing progressive CKD …

The progressive degeneration of the skeletal musculature in Duchenne muscular dystrophy
is accompanied by reactive myofibrosis, fat substitution, and chronic inflammation. Fibrotic …

Collagen, the most abundant structural protein found in mammals, plays a vital role as a
constituent of the extracellular matrix (ECM) that surrounds cells. Collagen fibrils are …

Chronic liver disease or repeated damage to hepatocytes can give rise to hepatic fibrosis.
Hepatic fibrosis (HF) is a pathological process of excessive sedimentation of extracellular …

The extracellular matrix (ECM) imparts critical mechanical and biochemical information to
cells in the lungs. Proteoglycans are essential constituents of the ECM and play a crucial …

This review focuses on the question of metabolic syndrome (MS) being a complex, but
essentially monophyletic, galaxy of associated diseases/disorders, or just a syndrome of …

Growth-related abnormalities affecting modern chickens, known as White Striping (WS) and
Wooden Breast (WB), have been deeply investigated in the last decade. Nevertheless, their …

Bioprosthetic heart valves (BHVs) are important for transcatheter valve replacement. Current
commercial BHVs on the market are basically porcine or bovine pericardium (BP) …