Progress in nasal drug delivery systems

F Laffleur, B Bauer - International Journal of Pharmaceutics, 2021 - Elsevier
Most of the available drugs are usually administered orally (eg in tablets or capsules) or by
parenteral injection in the case of substances being destroyed in the gastric environment or …

Potential pharmaceutical applications of quercetin in cardiovascular diseases

P Papakyriakopoulou, N Velidakis, E Khattab… - Pharmaceuticals, 2022 - mdpi.com
Quercetin, as a member of flavonoids, has emerged as a potential therapeutic agent in
cardiovascular diseases (CVDs) in recent decades. In this comprehensive literature review …

Enhancing the stability of zein/fucoidan composite nanoparticles with calcium ions for quercetin delivery

H Zhang, H Feng, J Ling, X Ouyang, X Song - International Journal of …, 2021 - Elsevier
In this study, zein and fucoidan-based composite nanoparticles were prepared by the
antisolvent precipitation method. The effects of different calcium ion (Ca 2+, 0–3.0 mM) …

Polyphenols as antioxidants for extending food shelf-life and in the prevention of health diseases: encapsulation and interfacial phenomena

M Costa, Z Sezgin-Bayindir, S Losada-Barreiro… - Biomedicines, 2021 - mdpi.com
Toxicity caused by the exposure to human-made chemicals and environmental conditions
has become a major health concern because they may significantly increase the formation …

[HTML][HTML] Quercetin, rutin and quercetin-rutin incorporated hydroxypropyl β-cyclodextrin inclusion complexes

E Başaran, AA Öztürk, B Şenel, M Demirel… - European journal of …, 2022 - Elsevier
Quercetin (Q) and rutin (R) are well known and most studied flavonoids due to their activities
in reduction of inflammation, oxidative damage, platelet aggregation and inhibition of cancer …

Quercetin: a potential polydynamic drug

N Georgiou, MG Kakava, EA Routsi, E Petsas… - Molecules, 2023 - mdpi.com
The study of natural products as potential drug leads has gained tremendous research
interest. Quercetin is one of those natural products. It belongs to the family of flavonoids and …

Quercetin: a bioactive compound imparting cardiovascular and neuroprotective benefits: scope for exploring fresh produce, their wastes, and by-products

IUH Bhat, R Bhat - Biology, 2021 - mdpi.com
Simple Summary The present review summarizes the generated hypothesis and critical role
of quercetin in cardiovascular and neuroprotective diseases reported over the last decade …

Micro-and nanosized carriers for nose-to-brain drug delivery in neurodegenerative disorders

R Boyuklieva, B Pilicheva - Biomedicines, 2022 - mdpi.com
Neurodegenerative disorders (NDs) have become a serious health problem worldwide due
to the rapid increase in the number of people that are affected and the constantly aging …

Resveratrol and cyclodextrins, an easy alliance: Applications in nanomedicine, green chemistry and biotechnology

P Jeandet, E Sobarzo-Sánchez, MS Uddin, R Bru… - Biotechnology …, 2021 - Elsevier
Most drugs or the natural substances reputed to display some biological activity are
hydrophobic molecules that demonstrate low bioavailability regardless of their mode of …

Protective effects of dietary quercetin on cerebral ischemic injury: pharmacology, pharmacokinetics and bioavailability-enhancing nanoformulations

Y Zhang, K Fu, C Wang, C Ma, L Gong, H Zhou… - Food & Function, 2023 - pubs.rsc.org
Cerebral ischemia, as an ischemic stroke-like disease, has become a health problem of
global concern. Studies have found that oxidative stress, inflammation, apoptosis, and …