LncRNA NNT-AS1/hsa-miR-485–5p/HSP90 axis in-silico and clinical prospect correlated-to histologic grades-based CRC stratification: A step toward ncRNA …
NM El-Sheikh, AI Abulsoud, A Fawzy, EF Wasfey… - … -Research and Practice, 2023 - Elsevier
The oncogenic effects of long non-coding RNA (lncRNA) Nicotinamide Nucleotide
Transhydrogenase-antisense RNA1 (NNT-AS1) role in colorectal cancer (CRC) hasn't been …
Transhydrogenase-antisense RNA1 (NNT-AS1) role in colorectal cancer (CRC) hasn't been …
FATCAT 2.0: towards a better understanding of the structural diversity of proteins
Abstract FATCAT 2.0 server (http://fatcat. godziklab. org/), provides access to a flexible
protein structure alignment algorithm developed in our group. In such an alignment …
protein structure alignment algorithm developed in our group. In such an alignment …
Nuclear envelope, chromatin organizers, histones, and DNA: The many achilles heels exploited across cancers
AK Balaji, S Saha, S Deshpande, D Poola… - Frontiers in Cell and …, 2022 - frontiersin.org
In eukaryotic cells, the genome is organized in the form of chromatin composed of DNA and
histones that organize and regulate gene expression. The dysregulation of chromatin …
histones that organize and regulate gene expression. The dysregulation of chromatin …
[HTML][HTML] The crystal structure of nsp10-nsp16 heterodimer from SARS-CoV-2 in complex with S-adenosylmethionine
M Rosas-Lemus, G Minasov, L Shuvalova, NL Inniss… - BioRxiv, 2020 - ncbi.nlm.nih.gov
SARS-CoV-2 is a member of the coronaviridae family and is the etiological agent of the
respiratory Coronavirus Disease 2019. The virus has spread rapidly around the world …
respiratory Coronavirus Disease 2019. The virus has spread rapidly around the world …
mTM-align: a server for fast protein structure database search and multiple protein structure alignment
With the rapid increase of the number of protein structures in the Protein Data Bank, it
becomes urgent to develop algorithms for efficient protein structure comparisons. In this …
becomes urgent to develop algorithms for efficient protein structure comparisons. In this …
Unusual structural and functional features of TpLRR/BspA-like LRR proteins
Abstract Leucine Rich Repeat (LRR) domains, are present in hundreds of thousands of
proteins across all kingdoms of life and are typically involved in protein–protein interactions …
proteins across all kingdoms of life and are typically involved in protein–protein interactions …
Cancer-associated circRNA–miRNA–mRNA Regulatory networks: a meta-analysis
Recent advances in sequencing technologies and the discovery of non-coding RNAs
(ncRNAs) have provided new insights in the molecular pathogenesis of cancers. Several …
(ncRNAs) have provided new insights in the molecular pathogenesis of cancers. Several …
PDBFlex: exploring flexibility in protein structures
The PDBFlex database, available freely and with no login requirements at http://pdbflex. org,
provides information on flexibility of protein structures as revealed by the analysis of …
provides information on flexibility of protein structures as revealed by the analysis of …
Mn2+ coordinates Cap-0-RNA to align substrates for efficient 2′-O-methyl transfer by SARS-CoV-2 nsp16
G Minasov, M Rosas-Lemus, L Shuvalova, NL Inniss… - Science …, 2021 - science.org
Capping of viral messenger RNAs is essential for efficient translation, for virus replication,
and for preventing detection by the host cell innate response system. The SARS-CoV-2 …
and for preventing detection by the host cell innate response system. The SARS-CoV-2 …
Dissecting protein domain variability in the core RNA interference machinery of five insect orders
FBM Arraes, D Martins-de-Sa, DD Noriega Vasquez… - RNA biology, 2021 - Taylor & Francis
ABSTRACT RNA interference (RNAi)-mediated gene silencing can be used to control
specific insect pest populations. Unfortunately, the variable efficiency in the knockdown …
specific insect pest populations. Unfortunately, the variable efficiency in the knockdown …