[HTML][HTML] Poly-l-lactic acid (PLLA)-based biomaterials for regenerative medicine: a review on processing and applications

E Capuana, F Lopresti, M Ceraulo, V La Carrubba - Polymers, 2022 - mdpi.com
Synthetic biopolymers are effective cues to replace damaged tissue in the tissue
engineering (TE) field, both for in vitro and in vivo application. Among them, poly-l-lactic acid …

3D extracellular matrix mimics: fundamental concepts and role of materials chemistry to influence stem cell fate

J Nicolas, S Magli, L Rabbachin, S Sampaolesi… - …, 2020 - ACS Publications
Synthetic 3D extracellular matrices (ECMs) find application in cell studies, regenerative
medicine, and drug discovery. While cells cultured in a monolayer may exhibit unnatural …

Recent progress on biodegradable tissue engineering scaffolds prepared by thermally-induced phase separation (Tips)

R Zeinali, LJ Del Valle, J Torras, J Puiggali - International journal of …, 2021 - mdpi.com
Porous biodegradable scaffolds provide a physical substrate for cells allowing them to
attach, proliferate and guide the formation of new tissues. A variety of techniques have been …

Solution-based processing for scaffold fabrication in tissue engineering applications: A brief review

E Capuana, F Lopresti, F Carfì Pavia, V Brucato… - Polymers, 2021 - mdpi.com
The fabrication of 3D scaffolds is under wide investigation in tissue engineering (TE)
because of its incessant development of new advanced technologies and the improvement …

Engineering hydrogels for the development of three-dimensional in vitro models

S Maji, H Lee - International Journal of Molecular Sciences, 2022 - mdpi.com
The superiority of in vitro 3D cultures over conventional 2D cell cultures is well recognized
by the scientific community for its relevance in mimicking the native tissue architecture and …

Hydrogels to engineer tumor microenvironments in vitro

K Fernando, LG Kwang, JTC Lim, ELS Fong - Biomaterials Science, 2021 - pubs.rsc.org
In recent years, hydrogel-based three-dimensional tumor models have become increasingly
mainstream for cancer research. Hydrogels enable recapitulation of biochemical and …

Investigating multi-material hydrogel three-dimensional printing for in vitro representation of the neo-vasculature of solid tumours: a comprehensive mechanical …

L Asciak, L Gilmour, JA Williams… - Royal Society …, 2023 - royalsocietypublishing.org
Many solid tumours (eg sarcoma, carcinoma and lymphoma) form a disorganized neo-
vasculature that initiates uncontrolled vessel formation to support tumour growth. The …

Evaluation of inhibitory effects of geniposide on a tumor model of human breast cancer based on 3D printed Cs/Gel hybrid scaffold

K Lv, J Zhu, S Zheng, Z Jiao, Y Nie, F Song… - Materials Science and …, 2021 - Elsevier
Traditional Chinese medicine therapy, which can serve as adjuvant therapy for cancer
treatment, has no obvious side effects on the human body. Geniposide (GEN), one of the …

PLLA Porous Scaffold as a 3D Breast Cancer Model to Investigate Drug Resistance

C Carbone, S Rigogliuso, VMB Brucato… - … Research Part A, 2025 - Wiley Online Library
Multidrug resistance remains one of the major challenges in breast cancer research, often
leading to treatment failure. To better understand this mechanism, sophisticated three …

[HTML][HTML] In vitro human cancer models for biomedical applications

JR Choi, G Kozalak, I Di Bari, Q Babar, Z Niknam… - Cancers, 2022 - mdpi.com
Simple Summary Cancer is a leading cause of death worldwide. While numerous studies
have been conducted on cancer treatment, clinical treatment options for cancers are still …