High prevalence of Pfcrt 76T and Pfmdr1 N86 genotypes in malaria infected patients attending health facilities in East Shewa zone, Oromia Regional State, Ethiopia

J Hassen, GS Alemayehu, H Dinka, L Golassa - Malaria Journal, 2022 - Springer
Background Plasmodium falciparum resistance to series of anti-malarial drugs is a major
challenge in efforts to control and/or eliminate malaria globally. In 1998, following the …

Genome-wide genetic variation and molecular surveillance of drug resistance in Plasmodium falciparum isolates from asymptomatic individuals in Ouélessébougou …

LN Vanheer, A Mahamar, E Manko, SM Niambele… - Scientific Reports, 2023 - nature.com
Sequence analysis of Plasmodium falciparum parasites is informative in ensuring sustained
success of malaria control programmes. Whole-genome sequencing technologies provide …

Genetic surveillance shows spread of ACT resistance during period of malaria decline in Vietnam (2018-2020)

JH Kattenberg, M Mutsaers, VH Nguyen… - Frontiers in …, 2024 - frontiersin.org
Introduction Vietnam's goal to eliminate malaria by 2030 is challenged by the further spread
of drug-resistant Plasmodium falciparum malaria to key antimalarials, particularly …

[HTML][HTML] Setting Up an NGS Sequencing Platform and Monitoring Molecular Markers of Anti-Malarial Drug Resistance in Djibouti

N Papa Mze, HY Arreh, RA Moussa, MB Elmi… - Biology, 2024 - mdpi.com
Djibouti is confronted with malaria resurgence, with malaria having been occurring in
epidemic proportions since a decade ago. The current epidemiology of drug-resistant …

Frequency of chloroquine-resistant haplotype of Plasmodium falciparum (CVIET) in Ibadan, Southwest Nigeria 17 years post-chloroquine withdrawal

A Amusan, O Akinola, K Akano… - Acta Tropica, 2024 - Elsevier
The replacement of chloroquine with artemisinin-based combination therapies (ACTs) for
over a decade has had varying impacts on the ability of the malaria parasite to sustain its …

Triple artemisinin-based combination therapy (TACT): Efficacy of dihydroartemisinin-piperaquine plus chloroquine against Plasmodium berghei ANKA strains with …

O Akinola, OO Afolabi, GO Adebisi-Jose… - Journal of Infection and …, 2024 - Elsevier
Background Evident detection of artemisinin resistance markers in patient isolates of
Plasmodium falciparum from East Africa threatens the efficacy of artemisinin-based …

[HTML][HTML] Moving population is a challenge for malaria elimination in India: A cross-sectional study to assess malaria parasite infections in walking pilgrims in western …

S Lata, SK Gupta, G Kumar, S Yadav, SS Mohanty… - IJID regions, 2024 - Elsevier
Objectives India is vigorously pursuing malaria elimination by 2030 and one of the key
challenges is how to prevent the malaria risk associated with long-distance migrations of …

The Role of Oral Chloroquine Treatment in the Home-Based Management of Childhood Malaria in Jos, Nigeria: Biochemical, Hematological, Nutritional, and Co …

SA Olomu, SY Gazuwa, T Johnson… - Advances in Infectious …, 2024 - scirp.org
Research Background: Malaria, predominantly caused by Plasmodium falciparum,
continues to be a leading cause of morbidity and mortality among children under five years …

Declining Frequency of Chloroquine-resistant Haplotype of Plasmodium falciparum (CVIET) in an Endemic Area of Southwest Nigeria 17 Years After Withdrawal of …

AI Amusan, O Akinola, K Akano… - 2023 - preprints.org
The replacement of chloroquine with artemisinin-based combination therapies (ACTs) for
over a decade has had varying impacts on the ability of malaria parasite to sustain its …

Genetic characterization of Plasmodium SPP and putative antimalarial drug resistant markers in the Central Region of Ghana

MP Dakorah - 2023 - ir.ucc.edu.gh
BACKGROUND: Malaria eradication is hampered by the genetic diversity of Plasmodium
falciparum, antimalarial resistance, and eco-geographical distinctions. The Central Region …