Abstract Hexavalent chromium (Cr (VI)), a commonly used industrial metal, is a well known
human lung carcinogen. Epidemiology and animal studies suggest that the particulate Cr …

The altered cellular gene expression profile is being hypothesized as the possible molecular
basis navigating the onset or progress of various morbidities. This hypothesis has been …

Abstract Heteroaromatic quinols 4-(benzothiazol-2-yl)-4-hydroxycyclohexa-2, 5-dienone (1)
and 4-(1-benzenesulfonyl-1 H-indol-2-yl)-4-hydroxycyclohexa-2, 5-dienone (2) exhibit …

The major genetic risk factor for Alzheimer's disease (AD), apolipoprotein E4 (ApoE4), has
been suggested to have detrimental effects on neurons, including direct toxicity via …

Early effects (only 1 h of exposure) of three isothiocyanates (benzyl, phenylethyl, and
sulforaphane) on nuclear accumulation of thioredoxin, APE/Ref-1, and transcription factors …

It is widely accepted that the chronic use of alcohol induces metabolic abnormalities and
neuronal damage in the brain, which can lead to cognitive dysfunction. Neuroimaging …

The mechanism of Cr (VI) genotoxicity has still not been elucidated. We used Fpg‐modified
comet assay to assess direct‐oxidative DNA damage on human lung (A549) and bronchial …

Abstract Hexavalent chromium (Cr (VI)) has been utilized for industrial applications for over
200 years. Due to its frequent use, workers in over 80 different industries are exposed to Cr …

The dietary phenolic compound, salicylic acid, decreases oxidative stress and pro-
inflammatory and potentially neo-plastic prostaglandins with a concomitant increase in …

Aryl chloroethylureas (CEUs) are potent anti-neoplastic agents alkylating specific
intracellular proteins such as βII-tubulin. Recently we have identified a new subset of CEU …