Decoding type I and III interferon signalling during viral infection

EV Mesev, RA LeDesma, A Ploss - Nature microbiology, 2019 - nature.com
Interferon (IFN)-mediated antiviral responses are central to host defence against viral
infection. Despite the existence of at least 20 IFNs, there are only three known cell surface …

Redox biology of respiratory viral infections

OA Khomich, SN Kochetkov, B Bartosch, AV Ivanov - Viruses, 2018 - mdpi.com
Respiratory viruses cause infections of the upper or lower respiratory tract and they are
responsible for the common cold—the most prevalent disease in the world. In many cases …

Progress in understanding and controlling respiratory syncytial virus: still crazy after all these years

PL Collins, JA Melero - Virus research, 2011 - Elsevier
Human respiratory syncytial virus (RSV) is a ubiquitous pathogen that infects everyone
worldwide early in life and is a leading cause of severe lower respiratory tract disease in the …

[HTML][HTML] Respiratory syncytial virus: from pathogenesis to potential therapeutic strategies

Z Shang, S Tan, D Ma - International Journal of Biological Sciences, 2021 - ncbi.nlm.nih.gov
Respiratory syncytial virus (RSV) is one of the most important viral pathogens causing
respiratory tract infection in infants, the elderly and people with poor immune function, which …

Deubiquitinating and interferon antagonism activities of coronavirus papain-like proteases

MA Clementz, Z Chen, BS Banach, Y Wang… - Journal of …, 2010 - Am Soc Microbiol
Coronaviruses encode multifunctional proteins that are critical for viral replication and for
blocking the innate immune response to viral infection. One such multifunctional domain is …

Immunological lessons from respiratory syncytial virus vaccine development

TJ Ruckwardt, KM Morabito, BS Graham - Immunity, 2019 - cell.com
Respiratory syncytial virus (RSV) has eluded active vaccination efforts for more than five
decades and continues to cause substantial morbidity and mortality in infants, the …

Biological challenges and technological opportunities for respiratory syncytial virus vaccine development

BS Graham - Immunological reviews, 2011 - Wiley Online Library
Respiratory syncytial virus (RSV) is an important cause of respiratory disease causing high
rates of hospitalizations in infants, significant morbidity in children and adults, and excess …

The morphology and assembly of respiratory syncytial virus revealed by cryo-electron tomography

Z Ke, RS Dillard, T Chirkova, F Leon, CC Stobart… - Viruses, 2018 - mdpi.com
Human respiratory syncytial virus (RSV) is the leading cause of lower respiratory tract
disease in young children. With repeat infections throughout life, it can also cause …

Toll-like receptors: key players in antiviral immunity

N Arpaia, GM Barton - Current opinion in virology, 2011 - Elsevier
TLRs are a family of innate receptors whose specificities are predetermined in the germline.
Therefore, TLRs have evolved to recognize conserved features of microbes. Viruses …

Respiratory syncytial virus nonstructural proteins 1 and 2: Exceptional disrupters of innate immune responses

K Sedeyn, B Schepens, X Saelens - PLoS pathogens, 2019 - journals.plos.org
Human respiratory syncytial virus (RSV) is the most important cause of acute lower
respiratory tract disease in infants worldwide. As a first line of defense against respiratory …