Current advance of nanotechnology in diagnosis and treatment for malignant tumors

B Wang, S Hu, Y Teng, J Chen, H Wang, Y Xu… - … and Targeted Therapy, 2024 - nature.com
Cancer remains a significant risk to human health. Nanomedicine is a new multidisciplinary
field that is garnering a lot of interest and investigation. Nanomedicine shows great potential …

Aptamer-based targeted delivery of functional nucleic acids

S Xie, W Sun, T Fu, X Liu, P Chen, L Qiu… - Journal of the …, 2023 - ACS Publications
Functional nucleic acid (NA)-based drugs have a broad range of applications since they
allow the alteration and control of gene/protein expression patterns in cells. In principle …

Aptamer-functionalized nanoparticles in targeted delivery and cancer therapy

Z Fu, J Xiang - International Journal of Molecular Sciences, 2020 - mdpi.com
Using nanoparticles to carry and delivery anticancer drugs holds much promise in cancer
therapy, but nanoparticles per se are lacking specificity. Active targeting, that is, using …

Exosomes and nanoengineering: a match made for precision therapeutics

PHL Tran, D Xiang, TTD Tran, W Yin… - Advanced …, 2020 - Wiley Online Library
Targeted exosomal delivery systems for precision nanomedicine attract wide interest across
areas of molecular cell biology, pharmaceutical sciences, and nanoengineering. Exosomes …

Triple negative breast cancer and non-small cell lung cancer: Clinical challenges and nano-formulation approaches

S Ghosh, A Javia, S Shetty, D Bardoliwala… - Journal of Controlled …, 2021 - Elsevier
Triple negative breast cancer (TNBC) and non-small cell lung cancer (NSCLC) are amongst
the most aggressive forms of solid tumors. TNBC is highlighted by absence of genetic …

Flavonoid nanoparticles: A promising approach for cancer therapy

M Dobrzynska, M Napierala, E Florek - Biomolecules, 2020 - mdpi.com
Flavonoids, a ubiquitous group of naturally occurring polyphenolic compounds, have
recently gained importance as anticancer agents. Unfortunately, due to low solubility …

Mucin1 and Mucin16: therapeutic targets for cancer therapy

DH Lee, S Choi, Y Park, H Jin - Pharmaceuticals, 2021 - mdpi.com
The mucin (MUC) family is a group of highly glycosylated macromolecules that are
abundantly expressed in mammalian epithelial cells. MUC proteins contribute to the …

Recent advances in flavonoid-based nanocarriers as an emerging drug delivery approach for cancer chemotherapy

S Dewanjee, P Chakraborty, H Bhattacharya… - Drug Discovery …, 2023 - Elsevier
Highlights•Flavonoids exhibit therapeutic potential against different types of cancer
cells.•Poor pharmacokinetics and biopharmaceutical traits limit their therapeutic …

Genistein as a regulator of signaling pathways and microRNAs in different types of cancers

Z Javed, K Khan, J Herrera-Bravo, S Naeem… - Cancer Cell …, 2021 - Springer
Cancers are complex diseases orchestrated by a plethora of extrinsic and intrinsic factors.
Research spanning over several decades has provided better understanding of complex …

[HTML][HTML] Targeting miRNAs by natural products: A new way for cancer therapy

B Zhang, L Tian, J Xie, G Chen, F Wang - Biomedicine & Pharmacotherapy, 2020 - Elsevier
MicroRNAs (miRNAs) are short non-coding RNAs that regulate gene expression through
mRNA degradation or translation inhibition. MiRNAs play important roles in a variety of …