Orodispersible dosage forms: Biopharmaceutical improvements and regulatory requirements
Highlights•Orodisperisible dosage forms improve the patient's compliance and/or
adherence.•Bioavailability must take in consideration the possible pre-gastric …
adherence.•Bioavailability must take in consideration the possible pre-gastric …
Liquisolid technology: A state-of-the-art review on the current state, challenges, new and emerging technologies for next generation
AM Agiba - Current Drug Delivery, 2020 - ingentaconnect.com
Nowadays, the focus has been shifted to new technologies for improving drug solubility,
permeability, and bioavailability, amid unprecedentedly increasing the number of newly …
permeability, and bioavailability, amid unprecedentedly increasing the number of newly …
[HTML][HTML] Study of rheological and tableting properties of lubricated mixtures of co-processed dry binders for orally disintegrating tablets
T Tranová, O Macho, J Loskot, J Mužíková - European Journal of …, 2022 - Elsevier
Co-processed dry binders for ODTs are important multifunctional excipients for tablet
manufacturing by direct compression. Testing their binary mixtures with lubricants is an …
manufacturing by direct compression. Testing their binary mixtures with lubricants is an …
Development of orally disintegrating tablets containing solid dispersion of a poorly soluble drug for enhanced dissolution: In-vitro optimization/in-vivo evaluation
Diacerein (DCN), a potent anti-inflammatory API used to treat osteoarthritis yet, it suffers from
poor water solubility which affects its oral absorption. Unabsorbed colonic DCN is converted …
poor water solubility which affects its oral absorption. Unabsorbed colonic DCN is converted …
A promising single oral disintegrating tablet for co-delivery of pitavastatin calcium and lornoxicam using co-processed excipients: formulation, characterization and …
Significance Statins are an important class of drugs that help to control hyperlipidemia, and
one of these statins recently used is pitavastatin calcium (PITA). Nevertheless, the most …
one of these statins recently used is pitavastatin calcium (PITA). Nevertheless, the most …
Evaluation and comparison of three types of spray dried coprocessed excipient Avicel® for direct compression
P Vodáčková, B Vraníková, P Svačinová… - BioMed Research …, 2018 - Wiley Online Library
As coprocessed excipients (CPE) gain a lot of focus recently, this article compares three
commercially available CPE of Avicel brand, namely, CE 15, DG, and HFE 102. Comparison …
commercially available CPE of Avicel brand, namely, CE 15, DG, and HFE 102. Comparison …
Investigating the impact of co-processed excipients on the formulation of bromhexine hydrochloride orally disintegrating tablets (ODTs)
K Woyna-Orlewicz, W Brniak, W Tatara… - Pharmaceutical …, 2023 - Springer
Purpose Orodispersible tablets (orally disintegrating tablets, ODTs) have been used in
pharmacotherapy for over 20 years since they overcome the problems with swallowing solid …
pharmacotherapy for over 20 years since they overcome the problems with swallowing solid …
Scalable flibanserin nanocrystal-based novel sublingual platform for female hypoactive sexual desire disorder: engineering, optimization adopting the desirability …
MJ Naguib, AIA Makhlouf - Drug Delivery, 2021 - Taylor & Francis
Flibanserin (FLB) was approved by FDA for the treatment of pre-menopausal female
hypoactive sexual desire disorder (HSDD). FLB suffers from low oral bioavailability (33%) …
hypoactive sexual desire disorder (HSDD). FLB suffers from low oral bioavailability (33%) …
Effect of co-processed excipient type on properties of orodispersible tablets containing captopril, tramadol, and domperidone
T Tranová, J Loskot, O Navrátil, W Brniak… - International Journal of …, 2023 - Elsevier
An important feature of orodispersible tablets (ODTs) is the convenient administration of the
drugs, in some cases, faster onset of action, stability maintenance, and dose precision. This …
drugs, in some cases, faster onset of action, stability maintenance, and dose precision. This …
Comprehensive study of co-processed excipients F-Melts®: Flow, viscoelastic and compacts properties
P Svačinová, B Vraníková, M Dominik, J Elbl… - Powder Technology, 2019 - Elsevier
This article aims to compare three commercially available co-processed excipients (CPEs),
namely the F-Melts® type C, M and F1. All three CPEs were subjected to the evaluation of …
namely the F-Melts® type C, M and F1. All three CPEs were subjected to the evaluation of …