Tryptophan, more than just an interfacial amino acid in the membrane activity of cationic cell-penetrating and antimicrobial peptides

S Khemaissa, A Walrant, S Sagan - Quarterly Reviews of Biophysics, 2022 - cambridge.org
Trp is unique among the amino acids since it is involved in many different types of
noncovalent interactions such as electrostatic and hydrophobic ones, but also in π-π, π …

The composition, internal interactions, auxiliary preparation methods, and applications of type five resistant starch: A review

T Zhou, Q Wang, Z Hu, J Huang, X Zheng, Y Tang… - Food …, 2024 - Elsevier
Starch, an essential polysaccharide, is pervasively employed in the food industry. However,
due to its low shear resistance, thermal susceptibility, and significant retrogradation …

Structural basis for sugar perception by Drosophila gustatory receptors

D Ma, M Hu, X Yang, Q Liu, F Ye, W Cai, Y Wang, X Xu… - Science, 2024 - science.org
Insects rely on a family of seven transmembrane proteins called gustatory receptors (GRs) to
encode different taste modalities, such as sweet and bitter. We report structures of …

The role of tryptophan in π interactions in proteins: an experimental approach

J Shao, BP Kuiper, AMWH Thunnissen… - Journal of the …, 2022 - ACS Publications
In proteins, the amino acids Phe, Tyr, and especially Trp are frequently involved in π
interactions such as π–π, cation− π, and CH− π bonds. These interactions are often crucial …

Quantification of protein glycosylation using nanopores

RCA Versloot, FLR Lucas, L Yakovlieva… - Nano Letters, 2022 - ACS Publications
Although nanopores can be used for single-molecule sequencing of nucleic acids using low-
cost portable devices, the characterization of proteins and their modifications has yet to be …

Exploration of Calocybe indica mushroom phenolic acid-kidney bean protein complex: Functional properties, amino acid profiles, in-vitro digestibility, and application …

ND Patil, S Thakur, A Bains, S Kaur, N Ali, R Arora… - Food Chemistry, 2024 - Elsevier
The study evaluates the interaction between Calocybe indica mushroom polyphenols
(phenolic acid) and kidney bean protein (KBPM), aiming to enhance vegan food quality. The …

Synthetic glycans reveal determinants of antibody functional efficacy against a fungal pathogen

CJ Crawford, L Guazzelli, SA McConnell… - ACS infectious …, 2023 - ACS Publications
Antibodies play a vital role in the immune response to infectious diseases and can be
administered passively to protect patients. In the case of Cryptococcus neoformans, a WHO …

Design of Glycopolymers for Controlling the Interactions with Lectins

M Nagao, H Matsumoto, Y Miura - Chemistry–An Asian Journal, 2023 - Wiley Online Library
Carbohydrates are involved in life activities through the interactions with their corresponding
proteins (lectins). Pathogen infection and the regulation of cell activity are controlled by the …

CH− π Interactions Are Required for Human Galectin-3 Function

RC Diehl, RS Chorghade, AM Keys, MM Alam… - JACS Au, 2024 - ACS Publications
Glycan-binding proteins, or lectins, recognize distinct structural elements of polysaccharides,
to mediate myriad biological functions. Targeting glycan-binding proteins involved in human …

Development of a GalNAc-Tyrosine-Specific Monoclonal Antibody and Detection of Tyrosine O-GalNAcylation in Numerous Human Tissues and Cell Lines

L Xia, TR Bellomo, R Gibadullin… - Journal of the …, 2022 - ACS Publications
Glycosylation is a vital post-translational modification involved in a range of biological
processes including protein folding, signaling, and cell–cell interactions. In 2011, a new type …