Thrombophilia is considered as a condition predisposing to the development of thrombosis.
Arterial thrombosis usually occurs after the erosion or rupture of an atherosclerotic plaque …

Objectives To evaluate the risk of venous thromboembolic events associated with the use of
progestin-only contraception and whether that risk differs with the mode of drug delivery …

Objective To examine the risk of non-fatal idiopathic venous thromboembolism in current
users of a combined oral contraceptive containing drospirenone, relative to current users of …

The use of oral contraceptives (OC) is a well established risk factor for venous thrombosis. It
has been known for many years that almost all haemostatic parameters ie plasma levels of …

Thrombin is the central enzyme in the coagulation cascade. Estimation of an individual's
potential to generate thrombin may correlate more closely with a hyper‐or hypo‐coagulable …

The recent development of semi-automated methods has revived interest in the thrombin
generation test, a global assay that measures the overall tendency of a plasma sample to …

Objective To compare the impact on thrombin generation of the new combined oral
contraceptive containing 15 mg estetrol and 3 mg drospirenone with ethinylestradiol (30 or …

Thrombosis is a deadly malfunctioning of the hemostatic system occurring in numerous
conditions and states, from surgery and pregnancy to cancer, sepsis and infarction. Despite …

We used the thrombin generation assay to evaluate the hypercoagulable state according to
JAK2 V617F mutational status in essential thrombocythemia (ET) and polycythemia vera …

Proteolytic inactivation of factors Va (FVa) and VIIIa (FVIIIa) by activated protein C (APC) and
its cofactors protein S and factor V (FV) is a key process in the physiological down …