Within the limited antifungal armamentarium, the azole antifungals are the most frequent
class used to treat Candida infections. Azole antifungals such as fluconazole are often …

There has been a sharp rise in the occurrence of Candida infections and associated
mortality over the last few years, due to the growing body of immunocompromised …

Invasive aspergillosis is a life-threatening mycosis caused by the pathogenic fungus
Aspergillus. The predominant causal species is Aspergillus fumigatus, and azole drugs are …

The growing prevalence of antifungal drug resistance coupled with the slow development of
new, acceptable drugs and fungicides has raised interest in natural products (NPs) for their …

Objectives: The purpose of this study was to characterize sets of extended-spectrum β-
lactamases (ESBL)-producing Enterobacteriaceae collected longitudinally from different …

Treatment of fungal infections is difficult due to several reasons, such as side effects of
drugs, emergence of resistant strains, and limited number of molecular targets for the drug …

Nicotinamide (NAM) has a long history in clinical applications and can be safely used for
treating various diseases. In recent years, NAM was found to exhibit antimicrobial activities …

Synergistic effects between the same class of antibiotics are rarely reported. Our previous
study found synergistic-like interaction between florfenicol (FFC) and thiamphenicol (TAP) …

Candida albicans is the most pathogenic fungal species, commonly colonizing on human
mucosal surfaces. As a polymorphic species, C. albicans is capable of switching between …

Objectives: Cryptococcus neoformans is an opportunistic fungus that causes fatal
meningoencephalitis especially in AIDS patients. There is an increasing need for discovery …