Bone stress injuries, including stress fractures, are overuse injuries that lead to substantial
morbidity in active individuals. These injuries occur when excessive repetitive loads are …

The mechanical properties of bone are fundamental to the ability of our skeletons to support
movement and to provide protection to our vital organs. As such, deterioration in mechanical …

Estrogens and androgens influence the growth and maintenance of the mammalian
skeleton and are responsible for its sexual dimorphism. Estrogen deficiency at menopause …

Overuse injuries in sport are thought to have a diverse and multifactorial etiology (1, 2), but
this is true only when overuse injury is defined at the whole-body, or systems, level. Overuse …

Bone fragility is a major health concern, as the increased risk of bone fractures has
devastating outcomes in terms of mortality, decreased autonomy, and healthcare costs …

Estrogen deficiency has been considered the seminal mechanism of osteoporosis in both
women and men, but epidemiological evidence in humans and recent mechanistic studies …

Osteoporosis, defined by the World Health Organization (WHO) as a bone mineral density
(BMD) T-score less than-2.5 as measured by dual-emission x-ray absorptiometry (DXA) is a …

Bone is a dynamic tissue that is constantly renewed. The cell populations that participate in
this process—the osteoblasts and osteoclasts—are derived from different progenitor pools …

This second edition of the Bone Mechanics Handbook summarizes the current
understanding of bone mechanics with comprehensive coverage of the histology …

Abstract Properties of the organic matrix of bone as well as its function in the microstructure
could be the key to the remarkable mechanical properties of bone. Previously, it was found …