Model systems for regeneration: planarians

M Ivankovic, R Haneckova, A Thommen… - …, 2019 - journals.biologists.com
Planarians are a group of flatworms. Some planarian species have remarkable regenerative
abilities, which involve abundant pluripotent adult stem cells. This makes these worms a …

Integrative biology of injury in animals

CW Rennolds, AE Bely - Biological Reviews, 2023 - Wiley Online Library
Mechanical injury is a prevalent challenge in the lives of animals with myriad potential
consequences for organisms, including reduced fitness and death. Research on animal …

Annelid adult cell type diversity and their pluripotent cellular origins

P Álvarez-Campos, H García-Castro, E Emili… - Nature …, 2024 - nature.com
Many annelids can regenerate missing body parts or reproduce asexually, generating all
cell types in adult stages. However, the putative adult stem cell populations involved in these …

Embryonic origins of adult pluripotent stem cells

JO Kimura, DM Bolaños, L Ricci, M Srivastava - Cell, 2022 - cell.com
Although adult pluripotent stem cells (aPSCs) are found in many animal lineages,
mechanisms for their formation during embryogenesis are unknown. Here, we leveraged …

Beyond casual resemblance: rigorous frameworks for comparing regeneration across species

M Srivastava - Annual Review of Cell and Developmental …, 2021 - annualreviews.org
The majority of animal phyla have species that can regenerate. Comparing regeneration
across animals can reconstruct the molecular and cellular evolutionary history of this …

Acoel single-cell atlas reveals expression dynamics and heterogeneity of adult pluripotent stem cells

RE Hulett, JO Kimura, DM Bolaños, YJ Luo… - Nature …, 2023 - nature.com
Adult pluripotent stem cell (aPSC) populations underlie whole-body regeneration in many
distantly-related animal lineages, but how the underlying cellular and molecular …

The sea spider Pycnogonum litorale overturns the paradigm of the absence of axial regeneration in molting animals

G Brenneis, K Frankowski, L Maaß… - Proceedings of the …, 2023 - National Acad Sciences
Regenerative abilities and their evolution in the different animal lineages have fascinated
generations of biologists. While some taxa are capable of restoring entire individuals from …

Whole-body regeneration in sponges: diversity, fine mechanisms, and future prospects

A Ereskovsky, IE Borisenko, FV Bolshakov, AI Lavrov - Genes, 2021 - mdpi.com
While virtually all animals show certain abilities for regeneration after an injury, these
abilities vary greatly among metazoans. Porifera (Sponges) is basal metazoans …

Comparative aspects of annelid regeneration: Towards understanding the mechanisms of regeneration

RP Kostyuchenko, VV Kozin - Genes, 2021 - mdpi.com
The question of why animals vary in their ability to regenerate remains one of the most
intriguing questions in biology. Annelids are a large and diverse phylum, many members of …

The brittle star genome illuminates the genetic basis of animal appendage regeneration

E Parey, O Ortega-Martinez, J Delroisse… - Nature Ecology & …, 2024 - nature.com
Species within nearly all extant animal lineages are capable of regenerating body parts.
However, it remains unclear whether the gene expression programme controlling …