Synergistic therapeutic strategies and engineered nanoparticles for anti-vascular endothelial growth factor therapy in cancer
Angiogenesis is one of the defining characteristics of cancer. Vascular endothelial growth
factor (VEGF) is crucial for the development of angiogenesis. A growing interest in cancer …
factor (VEGF) is crucial for the development of angiogenesis. A growing interest in cancer …
Research progress of bile biomarkers and their immunoregulatory role in biliary tract cancers
Y Li, K Li, Z Liu, Y Tang, XQ Hu, X Li, A Shi… - Frontiers in …, 2022 - frontiersin.org
Biliary tract cancers (BTCs), including cholangiocarcinoma and gallbladder carcinoma,
originate from the biliary epithelium and have a poor prognosis. Surgery is the only choice …
originate from the biliary epithelium and have a poor prognosis. Surgery is the only choice …
Histopathological growth pattern and vessel co-option in intrahepatic cholangiocarcinoma
Z Li, H Nguyen Canh, K Takahashi, D Le Thanh… - Medical Molecular …, 2024 - Springer
Intrahepatic cholangiocarcinoma (iCCA) exhibits different blood imaging features and
prognosis depending on histology. To clarity histopathological growth patterns (HGPs) and …
prognosis depending on histology. To clarity histopathological growth patterns (HGPs) and …
Targeting angiogenesis in the era of biliary tract cancer immunotherapy: biological rationale, clinical implications, and future research avenues
A Schirizzi, G De Leonardis, V Lorusso, R Donghia… - Cancers, 2023 - mdpi.com
Simple Summary The incidence of biliary tract cancers (BTCs) is rising. Although therapeutic
weapons are still limited, a better knowledge of the molecular landscape of these tumors has …
weapons are still limited, a better knowledge of the molecular landscape of these tumors has …
The role of tumor microenvironment in invasion and metastasis of esophageal squamous cell carcinoma
S Zheng, B Liu, X Guan - Frontiers in Oncology, 2022 - frontiersin.org
Esophageal squamous cell carcinoma (ESCC) is one of the most common cancers in the
world, with a high rate of morbidity. The invasion and metastasis of ESCC is the main reason …
world, with a high rate of morbidity. The invasion and metastasis of ESCC is the main reason …
SMAD4 regulates the progression of cholangiocarcinoma by modulating the expression of STING1
A Shi, L Zhao, G Sheng, G Zhang… - Journal of Cellular …, 2023 - Wiley Online Library
SMAD4 is a tumour suppressor and an important regulator of tumour immune scape which is
downregulated in cholangiocarcinoma (CCA). STING1 is a vital sensing factor of abnormal …
downregulated in cholangiocarcinoma (CCA). STING1 is a vital sensing factor of abnormal …
Protocol of REACH-01: a single-arm, open label, prospective study of HAIC sequential TAE combined with tislelizumab and surufatinib in unresectable intrahepatic …
K Li, Y Liu, T Zhang, Y Xu, Z Zhang - Frontiers in Pharmacology, 2024 - frontiersin.org
Introduction Gemcitabine and cisplatin remain the cornerstone for the treatment of advanced
or unresectable biliary tract cancers, but the incidence rate of the grade 3 or 4 toxic effects is …
or unresectable biliary tract cancers, but the incidence rate of the grade 3 or 4 toxic effects is …
Response Assessment of Primary Liver Tumors to Novel Therapies: an Imaging Perspective
The latest developments in cancer immunotherapy, namely the introduction of immune
checkpoint inhibitors, have led to a fundamental change in advanced cancer treatments …
checkpoint inhibitors, have led to a fundamental change in advanced cancer treatments …