Real-Time, In Vivo Molecular Monitoring Using Electrochemical Aptamer Based Sensors: Opportunities and Challenges
The continuous, real-time measurement of specific molecules in situ in the body would
greatly improve our ability to understand, diagnose, and treat disease. The vast majority of …
greatly improve our ability to understand, diagnose, and treat disease. The vast majority of …
An integrated wearable microneedle array for the continuous monitoring of multiple biomarkers in interstitial fluid
Implementations of wearable microneedle-based arrays of sensors for the monitoring of
multiple biomarkers in interstitial fluid have lacked system integration and evidence of robust …
multiple biomarkers in interstitial fluid have lacked system integration and evidence of robust …
Early prediction of circulatory failure in the intensive care unit using machine learning
Intensive-care clinicians are presented with large quantities of measurements from multiple
monitoring systems. The limited ability of humans to process complex information hinders …
monitoring systems. The limited ability of humans to process complex information hinders …
Electrochemical sensor for enzymatic lactate detection based on laser-scribed graphitic carbon modified with platinum, chitosan and lactate oxidase
We developed a flexible laser scribed graphitic carbon based lactate biosensor fabricated
using a low cost 450 nm laser. We demonstrated a facile fabrication method involving …
using a low cost 450 nm laser. We demonstrated a facile fabrication method involving …
Clinical challenges and opportunities related to the biological responses experienced by indwelling and implantable bioelectronic medical devices
Implantable electrodes have been utilized for decades to stimulate, sense, or monitor a
broad range of biological processes, with examples ranging from glucose monitoring …
broad range of biological processes, with examples ranging from glucose monitoring …
Monitoring of lactate in interstitial fluid, saliva and sweat by electrochemical biosensor: the uncertainties of biological interpretation
Lactate electrochemical biosensors were fabricated using Pediococcus sp lactate oxidase
(EC 1.1. 3.2), an external polyurethane membrane laminate diffusion barrier and an internal …
(EC 1.1. 3.2), an external polyurethane membrane laminate diffusion barrier and an internal …
Smart hydrogel micromechanical resonators with ultrasound readout for biomedical sensing
One of the main challenges for implantable biomedical sensing schemes is obtaining a
reliable signal while maintaining biocompatibility. In this work, we demonstrate that a …
reliable signal while maintaining biocompatibility. In this work, we demonstrate that a …
Monitoring with in vivo electrochemical sensors: navigating the complexities of blood and tissue reactivity
P Vadgama - Sensors, 2020 - mdpi.com
The disruptive action of an acute or critical illness is frequently manifest through rapid
biochemical changes that may require continuous monitoring. Within these changes, resides …
biochemical changes that may require continuous monitoring. Within these changes, resides …
Wearable microneedle sensor with replaceable sensor base for multi-purpose detecting in skin interstitial fluid
TQ Ma, QY He, XY Li, B Zhang, YL Li, LJ Chen… - Microchemical …, 2024 - Elsevier
The microneedle array provides a painless method for penetrating the skin to reach
interstitial fluid (ISF), making it suitable for drug delivery and monitoring of key biomarkers …
interstitial fluid (ISF), making it suitable for drug delivery and monitoring of key biomarkers …
Sweat lactate biosensor based on lactate oxidase immobilized with flower-like NiCo2O4 and carbon nanotubes
L Tian, L Cai, Z Ding, Y Zhou, Y Zhang, Q Liu, X Ge… - Microchemical …, 2024 - Elsevier
We design a portable and non-invasive lactate biosensor that can conveniently monitor
lactate levels in real human sweat. The proposed biosensor is constructed through the …
lactate levels in real human sweat. The proposed biosensor is constructed through the …