De novo gene birth
SB Van Oss, AR Carvunis - PLoS genetics, 2019 - journals.plos.org
De novo gene birth is the process by which new genes evolve from DNA sequences that
were ancestrally non-genic. De novo genes represent a subset of novel genes, and may be …
were ancestrally non-genic. De novo genes represent a subset of novel genes, and may be …
Conversion of DNA sequences: from a transposable element to a tandem repeat or to a gene
Eukaryotic genomes are rich in repetitive DNA sequences grouped in two classes regarding
their genomic organization: tandem repeats and dispersed repeats. In tandem repeats …
their genomic organization: tandem repeats and dispersed repeats. In tandem repeats …
Uncovering de novo gene birth in yeast using deep transcriptomics
WR Blevins, J Ruiz-Orera, X Messeguer… - Nature …, 2021 - nature.com
De novo gene origination has been recently established as an important mechanism for the
formation of new genes. In organisms with a large genome, intergenic and intronic regions …
formation of new genes. In organisms with a large genome, intergenic and intronic regions …
De novo gene integration into regulatory networks via interaction with conserved genes in peach
Y Cao, J Hong, Y Zhao, X Li, X Feng… - Horticulture …, 2024 - academic.oup.com
De novo genes can evolve “from scratch” from noncoding sequences, acquiring novel
functions in organisms and integrating into regulatory networks during evolution to drive …
functions in organisms and integrating into regulatory networks during evolution to drive …
A Continuum of Evolving De Novo Genes Drives Protein-Coding Novelty in Drosophila
Orphan genes, lacking detectable homologs in outgroup species, typically represent 10–
30% of eukaryotic genomes. Efforts to find the source of these young genes indicate that de …
30% of eukaryotic genomes. Efforts to find the source of these young genes indicate that de …
Population genomics reveals mechanisms and dynamics of de novo expressed open reading frame emergence in Drosophila melanogaster
A Grandchamp, L Kühl, M Lebherz… - Genome …, 2023 - genome.cshlp.org
Novel genes are essential for evolutionary innovations and differ substantially even between
closely related species. Recently, multiple studies across many taxa showed that some …
closely related species. Recently, multiple studies across many taxa showed that some …
Origins, evolution, and physiological implications of de novo genes in yeast
De novo gene birth is the process by which new genes emerge in sequences that were
previously noncoding. Over the past decade, researchers have taken advantage of the …
previously noncoding. Over the past decade, researchers have taken advantage of the …
Intergenic ORFs as elementary structural modules of de novo gene birth and protein evolution
The noncoding genome plays an important role in de novo gene birth and in the emergence
of genetic novelty. Nevertheless, how noncoding sequences' properties could promote the …
of genetic novelty. Nevertheless, how noncoding sequences' properties could promote the …
Movements of transposable elements contribute to the genomic plasticity and species diversification in an asexually reproducing nematode pest
DKL Kozlowski… - Evolutionary …, 2021 - Wiley Online Library
Despite reproducing without sexual recombination, Meloidogyne incognita is an adaptive
and versatile phytoparasitic nematode. This species displays a global distribution, can …
and versatile phytoparasitic nematode. This species displays a global distribution, can …
phylostratr: a framework for phylostratigraphy
Motivation The goal of phylostratigraphy is to infer the evolutionary origin of each gene in an
organism. This is done by searching for homologs within increasingly broad clades. The …
organism. This is done by searching for homologs within increasingly broad clades. The …