Membrane lipid homeostasis is a vital facet of bacterial cell physiology. For decades,
research in bacterial lipid synthesis was largely confined to the Escherichia coli model …

The accessory genes of Staphylococcus aureus, in‐cluding those involved in pathogenesis,
are controlled by a complex regulatory network that includes at least four two‐component …

Most bacteria have multiple peptidoglycan hydrolases capable of cleaving covalent bonds in
peptidoglycan sacculi or its fragments. An overview of the different classes of peptidoglycan …

Daptomycin (DAP) is a cyclic lipopeptide with in vitro activity against a variety of Gram‐
positive pathogens, including multidrug‐resistant organisms. Since its introduction into …

Two-component and phosphorelay signal transduction systems are the major means by
which bacteria recognize and respond to a variety of environmental stimuli. Recent results …

Antimicrobial resistance in Staphylococcus aureus is a major public health threat,
compounded by emergence of strains with resistance to vancomycin and daptomycin, both …

DNA microarray covering the whole genome of Staphylococcus aureus strain N315 was
prepared to investigate transcription profiles. The microarray analyses revealed that …

Two-component regulatory systems (TCSs) are a major mechanism by which bacteria sense
and respond to changes in their environment. TCSs typically consist of two proteins that …

Methicillin-resistant Staphylococcus aureus (MRSA) is one of the most prevalent bacterial
pathogens and continues to be a leading cause of morbidity and mortality worldwide. MRSA …

Daptomycin is a lipopeptide antibiotic with potent activity against gram-positive bacteria.
Complete-genome comparisons of laboratory-derived Staphylococcus aureus with …