Emerging insights in senescence: pathways from preclinical models to therapeutic innovations
L Mansfield, V Ramponi, K Gupta, T Stevenson… - npj Aging, 2024 - nature.com
Senescence is a crucial hallmark of ageing and a significant contributor to the pathology of
age-related disorders. As committee members of the young International Cell Senescence …
age-related disorders. As committee members of the young International Cell Senescence …
HRK downregulation and augmented BCL-xL binding to BAK confer apoptotic protection to therapy-induced senescent melanoma cells
C Alcon, M Kovatcheva, P Morales-Sánchez… - Cell Death & …, 2024 - nature.com
Senescent cells are commonly detected in tumors after chemo and radiotherapy, leading to
a characteristic cellular phenotype that resists apoptotic cell death. In this study, we used …
a characteristic cellular phenotype that resists apoptotic cell death. In this study, we used …
Genetic Evidence for Estrogenic Effects of Benzophenone-2 on Zebrafish Neurodevelopment and Its Signaling Mechanism
Z Qi, Y Zhai, Y Han, K Li, T Wang, P Li, J Li… - Environmental …, 2024 - ACS Publications
Estrogens play a crucial role in regulating various biological responses during the early
stages of neurodevelopment. Benzophenone-2 (BP2), a widely used organic ultraviolet (UV) …
stages of neurodevelopment. Benzophenone-2 (BP2), a widely used organic ultraviolet (UV) …