Trajectories of kidney function in diabetes: a clinicopathological update

M Oshima, M Shimizu, M Yamanouchi… - Nature Reviews …, 2021 - nature.com
Diabetic nephropathy has been traditionally diagnosed based on persistently high
albuminuria and a subsequent decline in glomerular filtration rate (GFR), which is widely …

Comparison of nonalbuminuric and albuminuric diabetic kidney disease among patients with type 2 diabetes: A systematic review and meta-analysis

S Shi, L Ni, L Gao, X Wu - Frontiers in Endocrinology, 2022 - frontiersin.org
Background Diabetic kidney disease (DKD) is one of most common complications of
diabetes. Recently, the classical phenotype of DKD, which is characterized by albuminuria …

Dietary flavonoid intake is associated with a lower risk of diabetic nephropathy in US adults: data from NHANES 2007–2008, 2009–2010, and 2017–2018

F Liu, J Nie, M Deng, H Yang, Q Feng, Y Yang, X Li… - Food & Function, 2023 - pubs.rsc.org
Few epidemiological studies have investigated the relationship between flavonoids and
diabetic nephropathy (DN). Therefore, we explored the association between dietary …

Recent advances in sensor arrays for the simultaneous electrochemical detection of multiple analytes

T Ozer, CS Henry - Journal of The Electrochemical Society, 2021 - iopscience.iop.org
In this review, electrochemical sensor arrays were investigated for various
chemical/biological sensing applications including proteins, whole cell pathogens, and …

Endothelial CXCR2 deficiency attenuates renal inflammation and glycocalyx shedding through NF-κB signaling in diabetic kidney disease

S Cui, X Chen, J Li, W Wang, D Meng, S Zhu… - Cell Communication and …, 2024 - Springer
Background The incidence of diabetic kidney disease (DKD) continues to rapidly increase,
with limited available treatment options. One of the hallmarks of DKD is persistent …

Mitochondrial DNA changes in blood and urine display a specific signature in relation to inflammation in normoalbuminuric diabetic kidney disease in type 2 diabetes …

L Petrica, A Vlad, F Gadalean, DM Muntean… - International Journal of …, 2023 - mdpi.com
Mitochondrial dysfunction is an important mechanism contributing to the development and
progression of diabetic kidney disease (DKD). Mitochondrial DNA (mtDNA) levels in blood …

Serum Cytokines and Growth Factors in Subjects with Type 1 Diabetes: Associations with Time in Ranges and Glucose Variability

VV Klimontov, KR Mavlianova, NB Orlov, JF Semenova… - Biomedicines, 2023 - mdpi.com
The detrimental effect of hyperglycemia and glucose variability (GV) on target organs in
diabetes can be implemented through a wide network of regulatory peptides. In this study …

Update on pathogenesis and diagnosis flow of normoalbuminuric diabetes with renal insufficiency

L Deng, W Li, G Xu - European journal of medical research, 2021 - Springer
In recent decades, the prevalence of diabetic kidney disease has remained stable and
appears to be a wide heterogeneity. Normoalbuminuric diabetes with renal insufficiency …

In vitro induction of eryptosis by uremic toxins and inflammation mediators in healthy red blood cells

GM Virzì, M Mattiotti, A Clementi… - Journal of Clinical …, 2022 - mdpi.com
Eryptosis is the stress-induced RBC (red blood cell) death mechanism. It is known that
eryptosis is largely influenced by plasma and blood composition, and that it is accelerated in …

Immune cell signatures and inflammatory mediators: unraveling their genetic impact on chronic kidney disease through Mendelian randomization

Y Hu, F Hao, Q An, W Jiang - Clinical and Experimental Medicine, 2024 - Springer
Prior research has established associations between immune cells, inflammatory proteins,
and chronic kidney disease (CKD). Our Mendelian randomization study aims to elucidate …